| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | PDE4C | Ser641 | YQSKIPRsPSDLTNP | phosphorylation down-regulates | 11030732 | SIGNOR-83187 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | PDE4C PSer641 | phosphorylation down-regulates ⊣ | PDE4C | 11030732 | SIGNOR-83187 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation down-regulates | PDE4C | SIGNOR-83187 |
