| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | PDE4D | Ser579 | YQSTIPQsPSPAPDD | phosphorylation down-regulates | 10828059 | SIGNOR-77563 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | PDE4D PSer579 | phosphorylation down-regulates ⊣ | PDE4D | 10828059 | SIGNOR-77563 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation down-regulates | PDE4D | SIGNOR-77563 |
