| Name | TFCP2 |
| ID | Q12800 |
| Role | substrate |
| Enzymatic Domains |
Grh/CP2 DB 61-300 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | TFCP2 | Ser291 | TYVNNSPsPGFNSSH | phosphorylation down-regulates | 19237534 | SIGNOR-184176 |
| ERK1/2 | TFCP2 | – | phosphorylation down-regulates | 19237534 | SIGNOR-270201 | |
| PPP2CA | TFCP2 | Ser291 | TYVNNSPsPGFNSSH | dephosphorylation up-regulates | 20682773 | SIGNOR-167385 |
| CDK2 | TFCP2 | Ser309 | SLGEGNGsPNHQPEP | phosphorylation down-regulates | 19237534 | SIGNOR-184160 |
| PPP2CA | TFCP2 | Ser309 | SLGEGNGsPNHQPEP | dephosphorylation up-regulates | 20682773 | SIGNOR-167389 |
| MAPK1 | TFCP2 | Ser291 | TYVNNSPsPGFNSSH | phosphorylation down-regulates | 19237534 | SIGNOR-184168 |
| MAPK3 | TFCP2 | Ser309 | SLGEGNGsPNHQPEP | phosphorylation down-regulates | 19237534 | SIGNOR-184180 |
| CyclinC/CDK3 | TFCP2 | Ser309 | SLGEGNGsPNHQPEP | phosphorylation down-regulates activity | 19237534 | SIGNOR-273180 |
| MAPK1 | TFCP2 | Ser309 | SLGEGNGsPNHQPEP | phosphorylation down-regulates | 19237534 | SIGNOR-184172 |
| CyclinE/CDK2 | TFCP2 | Ser309 | SLGEGNGsPNHQPEP | phosphorylation down-regulates | 19237534 | SIGNOR-216713 |
| Gbeta | TFCP2 | – | phosphorylation down-regulates | 19237534 | SIGNOR-270110 | |
| CDK3 | TFCP2 | Ser309 | SLGEGNGsPNHQPEP | phosphorylation down-regulates | 19237534 | SIGNOR-184164 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | TFCP2 PSer291 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-184176 |
| PPP2CA | dephosphorylation down-regulates ⊣ | TFCP2 PSer291 | dephosphorylation down-regulates ⊣ | TFCP2 | 20682773 | SIGNOR-167385 |
| CDK2 | phosphorylation up-regulates → | TFCP2 PSer309 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-184160 |
| PPP2CA | dephosphorylation down-regulates ⊣ | TFCP2 PSer309 | dephosphorylation down-regulates ⊣ | TFCP2 | 20682773 | SIGNOR-167389 |
| MAPK1 | phosphorylation up-regulates → | TFCP2 PSer291 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-184168 |
| MAPK3 | phosphorylation up-regulates → | TFCP2 PSer309 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-184180 |
| CyclinC/CDK3 | phosphorylation up-regulates → | TFCP2 PSer309 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-273180 |
| MAPK1 | phosphorylation up-regulates → | TFCP2 PSer309 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-184172 |
| CyclinE/CDK2 | phosphorylation up-regulates → | TFCP2 PSer309 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-216713 |
| CDK3 | phosphorylation up-regulates → | TFCP2 PSer309 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-184164 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation down-regulates | TFCP2 | SIGNOR-184176 |
| ERK1/2 | phosphorylation down-regulates | TFCP2 | SIGNOR-270201 |
| PPP2CA | dephosphorylation → up-regulates | TFCP2 | SIGNOR-167385 |
| CDK2 | phosphorylation down-regulates | TFCP2 | SIGNOR-184160 |
| PPP2CA | dephosphorylation → up-regulates | TFCP2 | SIGNOR-167389 |
| MAPK1 | phosphorylation down-regulates | TFCP2 | SIGNOR-184168 |
| MAPK3 | phosphorylation down-regulates | TFCP2 | SIGNOR-184180 |
| CyclinC/CDK3 | phosphorylation → down-regulates activity | TFCP2 | SIGNOR-273180 |
| MAPK1 | phosphorylation down-regulates | TFCP2 | SIGNOR-184172 |
| CyclinE/CDK2 | phosphorylation down-regulates | TFCP2 | SIGNOR-216713 |
| Gbeta | phosphorylation down-regulates | TFCP2 | SIGNOR-270110 |
| CDK3 | phosphorylation down-regulates | TFCP2 | SIGNOR-184164 |