| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | TFCP2 | Ser291 | TYVNNSPsPGFNSSH | dephosphorylation up-regulates | 20682773 | SIGNOR-167385 |
| MAPK1 | TFCP2 | Ser291 | TYVNNSPsPGFNSSH | phosphorylation down-regulates | 19237534 | SIGNOR-184168 |
| MAPK3 | TFCP2 | Ser291 | TYVNNSPsPGFNSSH | phosphorylation down-regulates | 19237534 | SIGNOR-184176 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | dephosphorylation down-regulates ⊣ | TFCP2 PSer291 | dephosphorylation down-regulates ⊣ | TFCP2 | 20682773 | SIGNOR-167385 |
| MAPK1 | phosphorylation up-regulates → | TFCP2 PSer291 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-184168 |
| MAPK3 | phosphorylation up-regulates → | TFCP2 PSer291 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-184176 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2CA | dephosphorylation → up-regulates | TFCP2 | SIGNOR-167385 |
| MAPK1 | phosphorylation down-regulates | TFCP2 | SIGNOR-184168 |
| MAPK3 | phosphorylation down-regulates | TFCP2 | SIGNOR-184176 |
