| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPM1D | TP53BP1 | Thr543 | IDEDGENtQIEDTEP | dephosphorylation down-regulates activity | 31619012 | SIGNOR-277046 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPM1D | dephosphorylation down-regulates ⊣ | TP53BP1 PThr543 | dephosphorylation up-regulates → | TP53BP1 | 31619012 | SIGNOR-277046 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPM1D | dephosphorylation → down-regulates activity | TP53BP1 | SIGNOR-277046 |
