Entity Details

Name EPS8
ID Q12929
Role substrate
Enzymatic Domains
PTB 64-194

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SH3 531-590
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTK6EPS8Tyr498YAFSSNIyTRGSHLDphosphorylation
up-regulates activity		27738316SIGNOR-263189
MAPK3EPS8Ser625
View in OncoXplorer
ADTPPAPsPPPTPAPphosphorylation
down-regulates activity		19564905SIGNOR-263058
PTK6EPS8Tyr535LKTQPKKyAKSKYDFphosphorylation
up-regulates activity		28214294SIGNOR-263191
PTK6EPS8Tyr525
View in OncoXplorer
NRHIDRNyEPLKTQPphosphorylation
up-regulates activity		28214294SIGNOR-263190
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTK6phosphorylation
up-regulates
→
EPS8
PTyr498		phosphorylation
up-regulates
→		EPS827738316SIGNOR-263189
MAPK3phosphorylation
up-regulates
→
EPS8
PSer625		phosphorylation
down-regulates
⊣		EPS819564905SIGNOR-263058
PTK6phosphorylation
up-regulates
→
EPS8
PTyr535		phosphorylation
up-regulates
→		EPS828214294SIGNOR-263191
PTK6phosphorylation
up-regulates
→
EPS8
PTyr525		phosphorylation
up-regulates
→		EPS828214294SIGNOR-263190
Regulator Mechanism/Effect Target SIGNOR-ID
PTK6phosphorylation
→
up-regulates activity 		EPS8SIGNOR-263189
MAPK3phosphorylation
→
down-regulates activity 		EPS8SIGNOR-263058
PTK6phosphorylation
→
up-regulates activity 		EPS8SIGNOR-263191
PTK6phosphorylation
→
up-regulates activity 		EPS8SIGNOR-263190