| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LCK | LCP2 | Tyr423 | NSLNEEWyVSYITRP | phosphorylation unknown | 8702662 | SIGNOR-251381 |
| ZAP70 | LCP2 | Tyr423 | NSLNEEWyVSYITRP | phosphorylation up-regulates | 8702662 | SIGNOR-42972 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LCK | phosphorylation up-regulates → | LCP2 PTyr423 | phosphorylation down-regulates ⊣ | LCP2 | 8702662 | SIGNOR-251381 |
| ZAP70 | phosphorylation up-regulates → | LCP2 PTyr423 | phosphorylation up-regulates → | LCP2 | 8702662 | SIGNOR-42972 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LCK | phosphorylation → unknown | LCP2 | SIGNOR-251381 |
| ZAP70 | phosphorylation → up-regulates | LCP2 | SIGNOR-42972 |
