| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP4K1 | LCP2 | Ser376 | SSFPQSAsLPPYFSQ | phosphorylation up-regulates | 17353368 | SIGNOR-153613 |
| MAP4K1 | LCP2 | Ser376 | PRKQLSESSDDDYDD | phosphorylation down-regulates activity | 17353368 | SIGNOR-274153 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP4K1 | phosphorylation up-regulates → | LCP2 PSer376 | phosphorylation up-regulates → | LCP2 | 17353368 | SIGNOR-153613 |
| MAP4K1 | phosphorylation up-regulates → | LCP2 PSer376 | phosphorylation down-regulates ⊣ | LCP2 | 17353368 | SIGNOR-274153 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAP4K1 | phosphorylation → up-regulates | LCP2 | SIGNOR-153613 |
| MAP4K1 | phosphorylation → down-regulates activity | LCP2 | SIGNOR-274153 |
