| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | REST | Ser1030 | MSEGSDDsGLHGARP | phosphorylation down-regulates activity | 25453754 | SIGNOR-279380 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | phosphorylation up-regulates → | REST PSer1030 | phosphorylation down-regulates ⊣ | REST | 25453754 | SIGNOR-279380 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK1 | phosphorylation → down-regulates activity | REST | SIGNOR-279380 |
