Entity Details

Name TARDBP
ID Q13148
Role substrate
Enzymatic Domains
RRM 1 104-200
PROSITE-ProRule
RRM 2 191-262
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
IKBKBTARDBPThr8MSEYIRVtEDENDEPphosphorylation
down-regulates quantity by destabilization		38197897SIGNOR-277861
IKBKBTARDBPSer92
View in OncoXplorer
MDETDASsAVKVKRAphosphorylation
down-regulates quantity by destabilization		38197897SIGNOR-277860
CDC7TARDBPSer410SSMDSKSsGWGMphosphorylation
up-regulates activity		23424178SIGNOR-278257
ABL1TARDBPTyr43PGACGLRyRNPVSQCphosphorylation
up-regulates quantity		36552734SIGNOR-279135
CDC7TARDBPSer409GSSMDSKsSGWGMphosphorylation
up-regulates activity		23424178SIGNOR-278256
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
IKBKBphosphorylation
up-regulates
→
TARDBP
PThr8		phosphorylation
down-regulates
⊣		TARDBP38197897SIGNOR-277861
IKBKBphosphorylation
up-regulates
→
TARDBP
PSer92		phosphorylation
down-regulates
⊣		TARDBP38197897SIGNOR-277860
CDC7phosphorylation
up-regulates
→
TARDBP
PSer410		phosphorylation
up-regulates
→		TARDBP23424178SIGNOR-278257
ABL1phosphorylation
up-regulates
→
TARDBP
PTyr43		phosphorylation
up-regulates
→		TARDBP36552734SIGNOR-279135
CDC7phosphorylation
up-regulates
→
TARDBP
PSer409		phosphorylation
up-regulates
→		TARDBP23424178SIGNOR-278256
Regulator Mechanism/Effect Target SIGNOR-ID
IKBKBphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		TARDBPSIGNOR-277861
IKBKBphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		TARDBPSIGNOR-277860
CDC7phosphorylation
→
up-regulates activity 		TARDBPSIGNOR-278257
ABL1phosphorylation
→
up-regulates quantity 		TARDBPSIGNOR-279135
CDC7phosphorylation
→
up-regulates activity 		TARDBPSIGNOR-278256