| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK2 | PAK2 | Ser20 | APPVRMSsTIFSTGG | phosphorylation up-regulates activity | 10075701 | SIGNOR-250227 |
| PRKAA2 | PAK2 | Ser20 | APPVRMSsTIFSTGG | phosphorylation unknown | 22137581 | SIGNOR-195110 |
| AMPK | PAK2 | Ser20 | APPVRMSsTIFSTGG | phosphorylation unknown | 22137581 | SIGNOR-216612 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK2 | phosphorylation up-regulates → | PAK2 PSer20 | phosphorylation up-regulates → | PAK2 | 10075701 | SIGNOR-250227 |
| PRKAA2 | phosphorylation up-regulates → | PAK2 PSer20 | phosphorylation down-regulates ⊣ | PAK2 | 22137581 | SIGNOR-195110 |
| AMPK | phosphorylation up-regulates → | PAK2 PSer20 | phosphorylation down-regulates ⊣ | PAK2 | 22137581 | SIGNOR-216612 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PAK2 | phosphorylation → up-regulates activity | PAK2 | SIGNOR-250227 |
| PRKAA2 | phosphorylation → unknown | PAK2 | SIGNOR-195110 |
| AMPK | phosphorylation → unknown | PAK2 | SIGNOR-216612 |
