Entity Details

Name CyclinK/CDK12_Thr134
ID Q13177
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK12PAK2Thr134LKFYDSNtVKQKYLSphosphorylation
up-regulates activity		32483448SIGNOR-273109
CyclinK/CDK12PAK2Thr134LKFYDSNtVKQKYLSphosphorylation
up-regulates activity		32483448SIGNOR-273111
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK12phosphorylation
up-regulates
→
PAK2
PThr134		phosphorylation
up-regulates
→		PAK232483448SIGNOR-273109
CyclinK/CDK12phosphorylation
up-regulates
→
PAK2
PThr134		phosphorylation
up-regulates
→		PAK232483448SIGNOR-273111
Regulator Mechanism/Effect Target SIGNOR-ID
CDK12phosphorylation
→
up-regulates activity 		PAK2SIGNOR-273109
CyclinK/CDK12phosphorylation
→
up-regulates activity 		PAK2SIGNOR-273111