| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK3 | STK3 | Thr180 | DTMAKRNtVIGTPFW | phosphorylation up-regulates | 20231902 | SIGNOR-164310 |
| PPP2CA | STK3 | Thr180 | DTMAKRNtVIGTPFW | dephosphorylation down-regulates | 23431053 | SIGNOR-201266 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK3 | phosphorylation up-regulates → | STK3 PThr180 | phosphorylation up-regulates → | STK3 | 20231902 | SIGNOR-164310 |
| PPP2CA | dephosphorylation down-regulates ⊣ | STK3 PThr180 | dephosphorylation up-regulates → | STK3 | 23431053 | SIGNOR-201266 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| STK3 | phosphorylation → up-regulates | STK3 | SIGNOR-164310 |
| PPP2CA | dephosphorylation down-regulates | STK3 | SIGNOR-201266 |
