| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | GRIN2B | Ser1166 | SDDFKRDsVSGGGPC | phosphorylation up-regulates activity | 24431445 | SIGNOR-276616 |
| PKA | GRIN2B | Ser1166 | SDDFKRDsVSGGGPC | phosphorylation up-regulates activity | 24431445 | SIGNOR-276617 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | GRIN2B PSer1166 | phosphorylation up-regulates → | GRIN2B | 24431445 | SIGNOR-276616 |
| PKA | phosphorylation up-regulates → | GRIN2B PSer1166 | phosphorylation up-regulates → | GRIN2B | 24431445 | SIGNOR-276617 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation → up-regulates activity | GRIN2B | SIGNOR-276616 |
| PKA | phosphorylation → up-regulates activity | GRIN2B | SIGNOR-276617 |