Entity Details

Name NR5A1
ID Q13285
Role substrate
Enzymatic Domains
NR LBD 222-459
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1NR5A1Ser203EYPEPYAsPPQPGLPphosphorylation
up-regulates activity		10230405SIGNOR-249431
TFIIHNR5A1Ser203EYPEPYAsPPQPGLPphosphorylation
up-regulates		17901130SIGNOR-269355
CLK4NR5A1Ser203EYPEPYAsPPQPGLPphosphorylation
up-regulates activity		35592512SIGNOR-274117
CDK7NR5A1Ser203EYPEPYAsPPQPGLPphosphorylation
up-regulates		17901130SIGNOR-157952
PTENNR5A1–dephosphorylation
down-regulates activity		27838257SIGNOR-277117
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
NR5A1
PSer203		phosphorylation
up-regulates
→		NR5A110230405SIGNOR-249431
TFIIHphosphorylation
up-regulates
→
NR5A1
PSer203		phosphorylation
up-regulates
→		NR5A117901130SIGNOR-269355
CLK4phosphorylation
up-regulates
→
NR5A1
PSer203		phosphorylation
up-regulates
→		NR5A135592512SIGNOR-274117
CDK7phosphorylation
up-regulates
→
NR5A1
PSer203		phosphorylation
up-regulates
→		NR5A117901130SIGNOR-157952
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
up-regulates activity 		NR5A1SIGNOR-249431
TFIIHphosphorylation
→
up-regulates 		NR5A1SIGNOR-269355
CLK4phosphorylation
→
up-regulates activity 		NR5A1SIGNOR-274117
CDK7phosphorylation
→
up-regulates 		NR5A1SIGNOR-157952
PTENdephosphorylation
→
down-regulates activity 		NR5A1SIGNOR-277117