| Name | SLAMF1 |
| ID | Q13291 |
| Role | substrate |
| Enzymatic Domains |
Ig-like V-type 29-138
Ig-like C2-type 144-223 |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LYN | SLAMF1 | Tyr327 | ETNSITVyASVTLPE | phosphorylation unknown | 15315965 | SIGNOR-127997 |
| FYN | SLAMF1 | Tyr327 | ETNSITVyASVTLPE | phosphorylation up-regulates activity | 11806999 | SIGNOR-251183 |
| FYN | SLAMF1 | Tyr281 | EKKSLTIyAQVQKPG | phosphorylation up-regulates activity | 11806999 | SIGNOR-251181 |
| FYN | SLAMF1 | Tyr307 | QDPCTTIyVAATEPV | phosphorylation up-regulates activity | 11806999 | SIGNOR-251182 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LYN | phosphorylation up-regulates → | SLAMF1 PTyr327 | phosphorylation down-regulates ⊣ | SLAMF1 | 15315965 | SIGNOR-127997 |
| FYN | phosphorylation up-regulates → | SLAMF1 PTyr327 | phosphorylation up-regulates → | SLAMF1 | 11806999 | SIGNOR-251183 |
| FYN | phosphorylation up-regulates → | SLAMF1 PTyr281 | phosphorylation up-regulates → | SLAMF1 | 11806999 | SIGNOR-251181 |
| FYN | phosphorylation up-regulates → | SLAMF1 PTyr307 | phosphorylation up-regulates → | SLAMF1 | 11806999 | SIGNOR-251182 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LYN | phosphorylation → unknown | SLAMF1 | SIGNOR-127997 |
| FYN | phosphorylation → up-regulates activity | SLAMF1 | SIGNOR-251183 |
| FYN | phosphorylation → up-regulates activity | SLAMF1 | SIGNOR-251181 |
| FYN | phosphorylation → up-regulates activity | SLAMF1 | SIGNOR-251182 |