| Name | ATM |
| ID | Q13315 |
| Role | kinase |
| Enzymatic Domains |
FAT 1940-2566 PROSITE-ProRule
PI3K/PI4K catalytic 2686-2998 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | AVEN | Ser135 | VNNESGEsQRGTDFS | phosphorylation up-regulates activity | 18571408 | SIGNOR-262636 |
| ATM | XRCC6 | Ser27 | QEENLEAsGDYKYSG | phosphorylation up-regulates activity | 26337656 | SIGNOR-274020 |
| ATM | UCK1 | – | phosphorylation down-regulates quantity by destabilization | 31938050 | SIGNOR-275963 | |
| ATM | USP28 | Ser714 | ESSTNSSsQDYSTSQ | phosphorylation down-regulates activity | 31938050 | SIGNOR-275853 |
| ATM | HIF1A | Ser696 | NVLSVALsQRTTVPE | phosphorylation up-regulates | 21095582 | SIGNOR-169999 |
| ATM | TOP2B | Ser1135 | HDDSSSDsGTPSGPD | phosphorylation down-regulates quantity by destabilization | 32015321 | SIGNOR-277510 |
| ATM | MDM4 | Ser342 | SKLTHSLsTSDITAI | phosphorylation down-regulates | 16943424 | SIGNOR-149292 |
| ATM | USP10 | Thr42 | SGTVLCGtQAVDKLP | phosphorylation up-regulates activity | 35627217 | SIGNOR-279795 |
| ATM | DCLRE1C | Ser645 | NLSTNADsQSSSDFE | phosphorylation up-regulates | 16874298 | SIGNOR-148323 |
| ATM | ATM | Ser2996 | QECKRNLsDIDQSFN | phosphorylation up-regulates activity | 21149446 | SIGNOR-170473 |
| ATM | ZFHX3 | Ser1180 | QEGGASSsQAEKELT | phosphorylation up-regulates activity | 21729327 | SIGNOR-279138 |
| ATM | IKBKG | Ser85 | ELLHFQAsQREEKEF | phosphorylation down-regulates activity | 16497931 | SIGNOR-144813 |
| ATM | MDM2 | Ser395 | SQESEDYsQPSTSSS | phosphorylation down-regulates activity | 11331603 | SIGNOR-107256 |
| ATM | KHSRP | Ser670 | GPGAPPGsQPDYSAA | phosphorylation up-regulates | 21329876 | SIGNOR-172127 |
| ATM | MDM2 | Ser395 | SQESEDYsQPSTSSS | phosphorylation down-regulates activity | 17936559 | SIGNOR-158324 |
| ATM | BRCA1 | Ser1524 | LQNRNYPsQEELIKV | phosphorylation up-regulates | 10550055 | SIGNOR-72068 |
| ATM | AATF | Ser189 | EGDDAEDsQGESEED | phosphorylation up-regulates quantity by stabilization | 17157788 | SIGNOR-264415 |
| ATM | ZNF148 | Ser202 | GEKPFQCsQCDMRFI | phosphorylation up-regulates | 17560543 | SIGNOR-155634 |
| ATM | TP53BP1 | Ser1219 | DDTESLHsQGEEEFD | phosphorylation up-regulates | 22621922 | SIGNOR-197611 |
| ATM | TP63 | Ser560 | LARLGCSsCLDYFTT | phosphorylation down-regulates | 18769144 | SIGNOR-180751 |
| ATM | CHEK2 | Ser33 | TQSQGSSsQSQGISS | phosphorylation up-regulates activity | 10973490 | SIGNOR-81399 |
| ATM | TP53 | Ser9 | EEPQSDPsVEPPLSQ | phosphorylation up-regulates quantity by stabilization | 11875057 | SIGNOR-115348 |
| ATM | FANCD2 | Ser1401 | LQGEEIKsQNSQEST | phosphorylation up-regulates | 12086603 | SIGNOR-90109 |
| ATM | MAD1L1 | Ser214 | KIQELQAsQEARADH | phosphorylation up-regulates activity | 24728176 | SIGNOR-278467 |
| ATM | BID | – | phosphorylation down-regulates activity | 23069655 | SIGNOR-279790 | |
| ATM | DGCR8 | Ser677 | RVGKQLAsQKILQLL | phosphorylation up-regulates quantity by stabilization | 34188037 | SIGNOR-277307 |
| ATM | MDM4 | Ser367 | PDCRRTIsAPVVRPK | phosphorylation down-regulates quantity by destabilization | 16943424 | SIGNOR-149296 |
| ATM | SP1 | Ser101 | DLTATQLsQGANGWQ | phosphorylation unknown | 18619531 | SIGNOR-179435 |
| ATM | USP28 | Ser67 | DERVKEPsQDTVATE | phosphorylation down-regulates activity | 31938050 | SIGNOR-275852 |
| ATM | PPM1G | Ser183 | GTGEEPGsQGLNGEA | phosphorylation up-regulates activity | 26324325 | SIGNOR-255591 |
| ATM | LAMTOR5 | – | phosphorylation up-regulates activity | 23667255 | SIGNOR-279791 | |
| ATM | TP53BP1 | Ser29 | IEDSQPEsQVLEDDS | phosphorylation unknown | 12697768 | SIGNOR-100645 |
| ATM | BLM | Thr99 | NAPAGQEtQRGGSKS | phosphorylation up-regulates | 12034743 | SIGNOR-88010 |
| ATM | DAXX | Ser564 | LEEESPVsQLFELEI | phosphorylation down-regulates | 23405218 | SIGNOR-200889 |
| ATM | HMGA1 | – | phosphorylation up-regulates activity | 18783938 | SIGNOR-279493 | |
| ATM | BCL10 | Thr91 | ESIRREKtQNFLIQK | phosphorylation up-regulates activity | 24732096 | SIGNOR-278392 |
| ATM | FANCA | Ser1449 | AAPDADLsQEPHLF | phosphorylation up-regulates | 19109555 | SIGNOR-182949 |
| ATM | BRCA1 | Ser1524 | LQNRNYPsQEELIKV | phosphorylation unknown | 10550055 | SIGNOR-72079 |
| ATM | EXO1 | – | phosphorylation up-regulates | 20019063 | SIGNOR-162304 | |
| ATM | METTL3 | Ser43 | RNPEAALsPTFRSDS | phosphorylation up-regulates activity | 32615088 | SIGNOR-265969 |
| ATM | NFAT5 | Ser1247 | AMQSNSPsQEQQQQQ | phosphorylation up-regulates | 15173573 | SIGNOR-125077 |
| ATM | PAN2 | Ser1003 | TKSTIKPsQMSVARI | phosphorylation up-regulates activity | 33097710 | SIGNOR-273508 |
| ATM | NOP53 | Ser233 | ARLHTKPsQAPAVEV | phosphorylation down-regulates quantity by destabilization | 27829214 | SIGNOR-273506 |
| ATM | XPA | Ser196 | RSLEVWGsQEALEEA | phosphorylation unknown | 16540648 | SIGNOR-250580 |
| ATM | FANCI | Ser730 | LDKSADFsQSTSIGI | phosphorylation unknown | 17412408 | SIGNOR-255590 |
| ATM | DCLRE1C | Ser503 | NDEITDEsLENFPSS | phosphorylation up-regulates | 16874298 | SIGNOR-148315 |
| ATM | TTC5 | Ser203 | TGQNPKIsQQALSAY | phosphorylation up-regulates activity | 15448695 | SIGNOR-262645 |
| ATM | TP53 | Ser20 | PLSQETFsDLWKLLP | phosphorylation up-regulates quantity by stabilization | 15254178 | SIGNOR-126757 |
| ATM | ELF4 | – | phosphorylation down-regulates activity | 21616937 | SIGNOR-278466 | |
| ATM | E2F1 | Ser31 | ALRLLDSsQIVIISA | phosphorylation up-regulates quantity by stabilization | 11459832 | SIGNOR-109416 |
| ATM | NKX3-1 | Thr166 | KNLKLTEtQVKIWFQ | phosphorylation down-regulates quantity by destabilization | 23890999 | SIGNOR-276500 |
| ATM | BRCA1 | Ser1423 | AVLEQHGsQPSNSYP | phosphorylation up-regulates | 10550055 | SIGNOR-72052 |
| ATM | BUB1 | Ser314 | SHEDLPAsQERSEVN | phosphorylation up-regulates | 22099307 | SIGNOR-177276 |
| ATM | SNAI1 | Ser100 | DEDSGKGsQPPSPPS | phosphorylation up-regulates activity | 23891091 | SIGNOR-279587 |
| ATM | BRCA1 | Ser1497 | EPGVERSsPSKCPSL | phosphorylation up-regulates | 10550055 | SIGNOR-72064 |
| ATM | RPA2 | Thr21 | YGGAGGYtQSPGGFG | phosphorylation unknown | 14872059 | SIGNOR-121865 |
| ATM | EZH2 | Ser729 | LFFDYRYsQADALKY | phosphorylation down-regulates quantity by destabilization | 24162653 | SIGNOR-276602 |
| ATM | DCK | Ser74 | EFEELTMsQKNGGNV | phosphorylation up-regulates activity | 27879648 | SIGNOR-275798 |
| ATM | POLL | Thr204 | EASDGEEtQVSAADL | phosphorylation up-regulates activity | 28109743 | SIGNOR-273510 |
| ATM | BRCA1 | Ser1542 | EEQQLEEsGPHDLTE | phosphorylation up-regulates | 10550055 | SIGNOR-72072 |
| ATM | BRCA1 | Ser1330 | QMRHQSEsQGVGLSD | phosphorylation up-regulates | 10550055 | SIGNOR-72048 |
| ATM | CHEK2 | Thr68 | SSLETVStQELYSIP | phosphorylation up-regulates activity | 16481012 | SIGNOR-276053 |
| ATM | KIFC1 | Ser26 | RPLIKAPsQLPLSGS | phosphorylation up-regulates quantity by stabilization | 33397932 | SIGNOR-277295 |
| ATM | MDM2 | Ser429 | KEESVESsLPLNAIE | phosphorylation down-regulates activity | 19816404 | SIGNOR-188412 |
| ATM | BRCA1 | Ser1497 | EPGVERSsPSKCPSL | phosphorylation up-regulates | 19683496 | SIGNOR-187591 |
| ATM | EZH2 | Ser734 | S-->L | phosphorylation down-regulates quantity | 24162653 | SIGNOR-279586 |
| ATM | TERF1 | Ser219 | SKLLMIIsQKDTFHS | phosphorylation up-regulates activity | 11375976 | SIGNOR-108419 |
| ATM | NBN | Ser343 | TTPGPSLsQGVSVDE | phosphorylation up-regulates | 10802669 | SIGNOR-77149 |
| ATM | FBXO31 | Ser278 | LMKFIYTsQYDNCLT | phosphorylation up-regulates | 19412162 | SIGNOR-185635 |
| ATM | H2AX | Ser140 | GKKATQAsQEY | phosphorylation up-regulates | 18158901 | SIGNOR-160206 |
| ATM | BRCA1 | – | phosphorylation up-regulates | 10550055 | SIGNOR-72075 | |
| ATM | POLL | Thr204 | EASDGEEtQVSAADL | phosphorylation up-regulates activity | 28109743 | SIGNOR-273836 |
| ATM | SMC1A | Ser957 | ISQEEGSsQGEDSVS | phosphorylation up-regulates | 11877377 | SIGNOR-115492 |
| ATM | ATM | Ser1981 | SLAFEEGsQSTTISS | phosphorylation up-regulates activity | 21149446 | SIGNOR-170469 |
| ATM | ATF1 | Ser51 | SSDSIGSsQKAHGIL | phosphorylation up-regulates activity | 20730097 | SIGNOR-278909 |
| ATM | CHEK1 | Ser345 | LVQGISFsQPTCPDH | phosphorylation up-regulates | 20068082 | SIGNOR-163110 |
| ATM | WRN | Ser1141 | PEKAYSSsQPVISAQ | phosphorylation unknown | 10608806 | SIGNOR-250577 |
| ATM | NABP2 | Thr117 | EPNPEYStQQAPNKA | phosphorylation up-regulates activity | 18449195 | SIGNOR-262639 |
| ATM | KHDC3L | Thr156 | VEVREAGtQRSVEVQ | phosphorylation up-regulates activity | 31609975 | SIGNOR-273504 |
| ATM | APLF | – | phosphorylation up-regulates activity | 18077224 | SIGNOR-279492 | |
| ATM | RELA | Ser547 | MDFSALLsQISS | phosphorylation down-regulates activity | 24957606 | SIGNOR-279006 |
| ATM | DCK | Ser74 | EFEELTMsQKNGGNV | phosphorylation up-regulates activity | 22850745 | SIGNOR-278221 |
| ATM | ATM | Ser367 | DTRSLEIsQSYTTTQ | phosphorylation up-regulates activity | 21149446 | SIGNOR-170477 |
| ATM | ITCH | Ser162 | TCSENGVsLCLPRLE | phosphorylation up-regulates activity | 23435430 | SIGNOR-276488 |
| ATM | MECOM | Ser1039 | NSNHGSQsPRNVEER | phosphorylation up-regulates activity | 29939287 | SIGNOR-273434 |
| ATM | ABL1 | Ser446 | PYPGIDLsQVYELLE | phosphorylation up-regulates | 9168116 | SIGNOR-48818 |
| ATM | NBN | Ser278 | VDTGITNsQTLIPDC | phosphorylation up-regulates | 10839544 | SIGNOR-78025 |
| ATM | NHEJ1 | Ser251 | ASLQGIDsQCVNQPE | phosphorylation unknown | 18644470 | SIGNOR-179528 |
| ATM | USP10 | Ser337 | ASGTLPVsQPKSWAS | phosphorylation up-regulates activity | 35627217 | SIGNOR-279796 |
| ATM | XPA | Ser173 | VKKNPHHsQWGDMKL | phosphorylation unknown | 16540648 | SIGNOR-250579 |
| ATM | TAOK1 | – | phosphorylation up-regulates | 17396146 | SIGNOR-154178 | |
| ATM | CREB1 | Thr100 | LKRLFSGtQISTIAE | phosphorylation down-regulates | 15073328 | SIGNOR-124051 |
| ATM | ZEB1 | Ser585 | GDGNLSPsQPPLKNL | phosphorylation up-regulates activity | 25086746 | SIGNOR-278329 |
| ATM | TAOK1 | Thr785 | SINEMLStQALRLDE | phosphorylation up-regulates | 17396146 | SIGNOR-154175 |
| ATM | MDM2 | Ser395 | SQESEDYsQPSTSSS | phosphorylation down-regulates activity | 12383858 | SIGNOR-94268 |
| ATM | TP53 | Ser46 | AMDDLMLsPDDIEQW | phosphorylation up-regulates quantity by stabilization | 11875057 | SIGNOR-115344 |
| ATM | KAT8 | Thr392 | LSQMTSItQNDIIST | phosphorylation up-regulates activity | 24953651 | SIGNOR-278350 |
| ATM | WRAP53 | Ser64 | PVAGSAVsQELREGD | phosphorylation up-regulates activity | 27715493 | SIGNOR-273511 |
| ATM | XRCC6 | Ser33 | ASGDYKYsGRDSLIF | phosphorylation up-regulates activity | 26337656 | SIGNOR-274021 |
| ATM | NFAT5 | Ser1367 | LVQGSPSsQEQQVTL | phosphorylation up-regulates | 15173573 | SIGNOR-125081 |
| ATM | PNKP | Ser114 | EETRTPEsQPDTPPG | phosphorylation up-regulates | 21824916 | SIGNOR-176008 |
| ATM | NPM1 | – | phosphorylation up-regulates activity | 21499441 | SIGNOR-280182 | |
| ATM | RAD9A | Ser272 | LSDTDSHsQDLGSPE | phosphorylation up-regulates activity | 11278446 | SIGNOR-105243 |
| ATM | PRKDC | Thr2609 | LTPMFVEtQASQGTL | phosphorylation up-regulates | 17189255 | SIGNOR-151441 |
| ATM | UCHL3 | Ser75 | EEEEKIKsQGQDVTS | phosphorylation up-regulates activity | 27941124 | SIGNOR-275910 |
| ATM | FBXW7 | Ser26 | LRGNPSSsQVDEEQM | phosphorylation up-regulates activity | 26774286 | SIGNOR-259942 |
| ATM | NBN | Ser615 | VPESSKIsQENEIGK | phosphorylation up-regulates | 10839545 | SIGNOR-78034 |
| ATM | RBBP8 | Ser664 | IDPGADLsQYKMDVT | phosphorylation down-regulates | 10910365 | SIGNOR-79872 |
| ATM | RNF20 | – | phosphorylation up-regulates | 21763684 | SIGNOR-174949 | |
| ATM | USP24 | – | phosphorylation up-regulates activity | 25578727 | SIGNOR-280043 | |
| ATM | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates quantity by stabilization | 15254178 | SIGNOR-126753 |
| ATM | KHDC3L | Thr145 | IEVREAGtQRSVEVR | phosphorylation up-regulates activity | 31609975 | SIGNOR-273505 |
| ATM | TP63 | Thr491 | PQQRNALtPTTIPDG | phosphorylation down-regulates | 18769144 | SIGNOR-180755 |
| ATM | PEX5 | Ser141 | DYNETDWsQEFISEV | phosphorylation up-regulates activity | 26344566 | SIGNOR-262792 |
| ATM | ATM | Ser440 | SPLLMILsQLLPQQR | phosphorylation unknown | 10608806 | SIGNOR-250576 |
| ATM | UCHL3 | – | phosphorylation up-regulates activity | 27941124 | SIGNOR-279794 | |
| ATM | PPP2R5D | – | phosphorylation up-regulates activity | 21460856 | SIGNOR-276319 | |
| ATM | ATM | Ser1893 | PANLDSEsEHFFRCC | phosphorylation up-regulates activity | 21149446 | SIGNOR-170465 |
| ATM | EP300 | Ser106 | GPGQVMAsQAQQSSP | phosphorylation up-regulates | 20471956 | SIGNOR-165567 |
| ATM | CDKN1B | Ser140 | PKTDPSDsQTGLAEQ | phosphorylation up-regulates quantity by stabilization | 27611996 | SIGNOR-279392 |
| ATM | DYRK2 | Thr106 | NKRTVLTtQPNGLTT | phosphorylation up-regulates quantity by stabilization | 19965871 | SIGNOR-275576 |
| ATM | H2AX | Ser140 | GKKATQAsQEY | phosphorylation up-regulates | 21690091 | SIGNOR-174442 |
| ATM | SIAH1 | Ser19 | GTSKCPPsQRVPALT | phosphorylation down-regulates | 18536714 | SIGNOR-177945 |
| ATM | PPP2R5C | – | phosphorylation up-regulates activity | 21460856 | SIGNOR-276320 | |
| ATM | CHEK2 | Ser50 | TSTMPNSsQSSHSSS | phosphorylation up-regulates activity | 10973490 | SIGNOR-81407 |
| ATM | AGER | Ser391 | ERAELNQsEEPEAGE | phosphorylation up-regulates activity | 28977635 | SIGNOR-278907 |
| ATM | RNF40 | – | phosphorylation up-regulates | 21763684 | SIGNOR-175003 | |
| ATM | RNF40 | Ser114 | ALLRCHEsQGELSSA | phosphorylation up-regulates activity | 21362549 | SIGNOR-276315 |
| ATM | BRCA1 | – | phosphorylation up-regulates | 12024016 | SIGNOR-87845 | |
| ATM | PRKAA2 | Thr172 | SDGEFLRtSCGSPNY | phosphorylation up-regulates activity | 23871434 | SIGNOR-275488 |
| ATM | MRE11 | Ser264 | EQQLFYIsQPGSSVV | phosphorylation up-regulates | 10608806 | SIGNOR-73366 |
| ATM | CCAR2 | Thr454 | AAEAAPPtQEAQGET | phosphorylation up-regulates activity | 22735644 | SIGNOR-267661 |
| ATM | USP28 | – | phosphorylation up-regulates activity | 31938050 | SIGNOR-279007 | |
| ATM | SMC1A | Ser966 | GEDSVSGsQRISSIY | phosphorylation up-regulates | 11877377 | SIGNOR-115496 |
| ATM | PNKP | Ser126 | PPGTPLVsQDEKRDA | phosphorylation up-regulates | 21824916 | SIGNOR-176012 |
| ATM | USP10 | Thr42 | SGTVLCGtQAVDKLP | phosphorylation up-regulates quantity by stabilization | 20096447 | SIGNOR-276275 |
| ATM | DYRK2 | Ser442 | IELLGMPsQKLLDAS | phosphorylation up-regulates quantity by stabilization | 19965871 | SIGNOR-275577 |
| ATM | CHEK2 | Thr68 | SSLETVStQELYSIP | phosphorylation up-regulates activity | 10973490 | SIGNOR-81438 |
| ATM | AVEN | Ser308 | NILPDQTsQDLKSKE | phosphorylation up-regulates activity | 18571408 | SIGNOR-262637 |
| ATM | RNF20 | Ser172 | SSSEEMEsQLQERVE | phosphorylation up-regulates activity | 21362549 | SIGNOR-276314 |
| ATM | MDC1 | – | phosphorylation up-regulates | 12607003 | SIGNOR-98798 | |
| ATM | TP53 | Ser20 | PLSQETFsDLWKLLP | phosphorylation up-regulates quantity by stabilization | 20663147 | SIGNOR-167156 |
| ATM | MDM4 | Ser403 | DLAHSSEsQETISSM | phosphorylation down-regulates | 16943424 | SIGNOR-149300 |
| ATM | TP53BP1 | Ser25 | PCLIIEDsQPESQVL | phosphorylation unknown | 12697768 | SIGNOR-100641 |
| ATM | SMAD1 | Ser239 | DPMTQDGsQPMDTNM | phosphorylation up-regulates | 22588298 | SIGNOR-197533 |
| ATM | RNF138 | Ser124 | IIPNFQIsQDSVGNS | phosphorylation up-regulates activity | 27195665 | SIGNOR-279505 |
| ATM | TP53 | – | phosphorylation up-regulates quantity by stabilization | 17157788 | SIGNOR-151138 | |
| ATM | CHEK2 | Ser19 | SHGSSACsQPHGSVT | phosphorylation up-regulates activity | 10973490 | SIGNOR-81391 |
| ATM | ABRAXAS1 | Ser404 | MKGFGEYsRSPTF | phosphorylation up-regulates activity | 26778126 | SIGNOR-255587 |
| ATM | TP53BP1 | Ser831 | EPVEQDSsQPSLPLV | phosphorylation up-regulates | 22621922 | SIGNOR-197615 |
| ATM | BRD7 | Ser263 | QKDGTDTsQSGEDGG | phosphorylation down-regulates activity | 33101843 | SIGNOR-279780 |
| ATM | MPG | Ser172 | YFCMNISsQGDGACV | phosphorylation up-regulates activity | 25100205 | SIGNOR-279004 |
| ATM | HNF1A | Ser249 | IQRGVSPsQAQGLGS | phosphorylation up-regulates | 24821553 | SIGNOR-205087 |
| ATM | LARP7 | Thr440 | ANREECRtQEKVNAT | phosphorylation down-regulates quantity by destabilization | 32726637 | SIGNOR-275580 |
| ATM | WRN | Ser1292 | MTIGMHLsQAVKAGC | phosphorylation unknown | 10608806 | SIGNOR-250578 |
| ATM | MDM4 | – | phosphorylation down-regulates | 16082221 | SIGNOR-139403 | |
| ATM | DBF4 | Thr449 | DDIRQNFtQLPLHKN | phosphorylation down-regulates | 22123827 | SIGNOR-177801 |
| ATM | CREB1 | Ser107 | SVDSVTDsQKRREIL | phosphorylation down-regulates | 15073328 | SIGNOR-124047 |
| ATM | L3MBTL2 | – | phosphorylation up-regulates activity | 31225475 | SIGNOR-266785 | |
| ATM | STK11 | Thr367 | IIYTQDFtVPGQVPE | phosphorylation up-regulates | 12234250 | SIGNOR-92873 |
| ATM | ACTR8 | Ser412 | MTTLQHRsQGDPEDP | phosphorylation down-regulates activity | 29759113 | SIGNOR-279437 |
| ATM | ATF2 | Ser498 | QIVMAPSsQSQPSGS | phosphorylation up-regulates | 15916964 | SIGNOR-137623 |
| ATM | NKX3-1 | – | phosphorylation down-regulates quantity | 23890999 | SIGNOR-279726 | |
| ATM | TDP1 | Ser81 | PKRQKSGsQEDLGWC | phosphorylation up-regulates | 19851285 | SIGNOR-188772 |
| ATM | ZNF420 | Ser68 | NTYETELsQWEMSDR | phosphorylation down-regulates activity | 19377469 | SIGNOR-273513 |
| ATM | TAOK1 | Thr643 | EELNKRQtQKDLEHA | phosphorylation up-regulates | 17396146 | SIGNOR-154171 |
| ATM | PLK1 | – | phosphorylation down-regulates activity | 20042274 | SIGNOR-279793 | |
| ATM | UBQLN4 | Ser318 | GNSDSSSsQPLRTEN | phosphorylation up-regulates activity | 30612738 | SIGNOR-265076 |
| ATM | MDM2 | Ser386 | DDKITQAsQSQESED | phosphorylation down-regulates activity | 19816404 | SIGNOR-188408 |
| ATM | SMC3 | Ser1083 | ESERGSGsQSSVPSV | phosphorylation unknown | 18442975 | SIGNOR-178479 |
| ATM | FANCD2 | Ser222 | LPEILGDsQHADVGK | phosphorylation up-regulates | 12086603 | SIGNOR-90121 |
| ATM | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates quantity by stabilization | 11875057 | SIGNOR-115340 |
| ATM | RRM2B | Ser72 | TAEEVDLsKDLPHWN | phosphorylation up-regulates | 19015526 | SIGNOR-182423 |
| ATM | CSNK1D | – | phosphorylation up-regulates activity | 22976441 | SIGNOR-279504 | |
| ATM | BTRC | Ser158 | EFVEHLIsQMCHYQH | phosphorylation up-regulates quantity by stabilization | 33676897 | SIGNOR-277549 |
| ATM | STK11 | Thr363 | IEDDIIYtQDFTVPG | phosphorylation unknown | 12234250 | SIGNOR-92877 |
| ATM | RAD17 | Ser646 | ETWSLPLsQNSASEL | phosphorylation unknown | 10608806 | SIGNOR-73520 |
| ATM | BRCA1 | Ser1387 | EDCSGLSsQSDILTT | phosphorylation up-regulates | 12183412 | SIGNOR-91482 |
| ATM | PPP2R5C | Ser520 | CRADELAsQDGR | phosphorylation up-regulates activity | 21460856 | SIGNOR-276318 |
| ATM | BRCA1 | Ser1457 | SEKAVLTsQKSSEYP | phosphorylation up-regulates | 10550055 | SIGNOR-72056 |
| ATM | FANCD2 | Ser1407 | KSQNSQEsTADESED | phosphorylation up-regulates | 12086603 | SIGNOR-90117 |
| ATM | PIDD1 | Thr788 | DAETGFLtQSNLLSV | phosphorylation up-regulates activity | 22854598 | SIGNOR-262640 |
| ATM | BRCA1 | Ser1466 | KSSEYPIsQNPEGLS | phosphorylation up-regulates | 10550055 | SIGNOR-72060 |
| ATM | COP1 | Ser387 | SDDSRTAsQLDEFQE | phosphorylation down-regulates | 16931761 | SIGNOR-149082 |
| ATM | RASSF1 | Ser135 | EWETPDLsQAEIEQK | phosphorylation up-regulates | 19962312 | SIGNOR-161934 |
| ATM | UFL1 | Ser462 | DDDSDDEsQSSHTGK | phosphorylation up-regulates activity | 30886146 | SIGNOR-265075 |
| ATM | CREB1 | Ser97 | TIAESEDsQESVDSV | phosphorylation down-regulates activity | 15073328 | SIGNOR-124043 |
| ATM | CHEK2 | Thr26 | SQPHGSVtQSQGSSS | phosphorylation up-regulates activity | 12024051 | SIGNOR-87850 |
| ATM | IPO9 | – | phosphorylation up-regulates activity | 26943034 | SIGNOR-278910 | |
| ATM | NOP53 | Thr289 | PATEQAAtQESTFQE | phosphorylation down-regulates quantity by destabilization | 27829214 | SIGNOR-273507 |
| ATM | NBN | Ser397 | EQKFRMLsQDAPTVK | phosphorylation up-regulates | 10839545 | SIGNOR-78030 |
| ATM | TAOK1 | Ser990 | SRSTSVTsQISNGSH | phosphorylation up-regulates | 17396146 | SIGNOR-154167 |
| ATM | NKX3-1 | Thr134 | SRAAFSHtQVIELER | phosphorylation down-regulates quantity by destabilization | 23890999 | SIGNOR-276499 |
| ATM | TP53BP1 | Ser6 | sQLDSDFS | phosphorylation unknown | 12697768 | SIGNOR-100649 |
| ATM | TP53BP1 | – | phosphorylation up-regulates | 22621922 | SIGNOR-197622 | |
| ATM | DBF4 | Ser539 | GLITINSsQEHLTVQ | phosphorylation down-regulates | 22123827 | SIGNOR-177797 |
| ATM | DCLRE1C | Ser516 | SSTVAGGsQSPKLFS | phosphorylation up-regulates | 16874298 | SIGNOR-148319 |
| ATM | TP63 | Ser477 | NSMNKLPsVSQLINP | phosphorylation down-regulates | 18769144 | SIGNOR-180747 |
| ATM | TP53BP1 | Ser784 | GVEKCSDsQSWEDIA | phosphorylation unknown | 12697768 | SIGNOR-100653 |
| ATM | DBF4 | Ser502 | FSTDNSGsQPKQKSD | phosphorylation down-regulates | 22123827 | SIGNOR-177793 |
| ATM | ATF2 | Ser490 | QSTEPALsQIVMAPS | phosphorylation up-regulates | 15916964 | SIGNOR-137619 |
| ATM | NBN | Ser343 | TTPGPSLsQGVSVDE | phosphorylation up-regulates | 10608806 | SIGNOR-73432 |
| ATM | BUB3 | Ser135 | PCNAGTFsQPEKVYT | phosphorylation up-regulates activity | 35085551 | SIGNOR-277582 |
| ATM | TP53 | Ser20 | PLSQETFsDLWKLLP | phosphorylation up-regulates quantity by stabilization | 17967874 | SIGNOR-158636 |
| ATM | TP53BP1 | Thr302 | PEPEVLStQEDLFDQ | phosphorylation up-regulates | 22621922 | SIGNOR-197619 |
| ATM | SMC1A | Ser966 | GEDSVSGsQRISSIY | phosphorylation up-regulates activity | 11877376 | SIGNOR-255589 |
| ATM | NFAT5 | Ser1197 | HIQTPMLsQEQAQPP | phosphorylation up-regulates | 15173573 | SIGNOR-125073 |
| ATM | KHSRP | Ser274 | MILIQDGsQNTNVDK | phosphorylation up-regulates | 21329876 | SIGNOR-172123 |
| ATM | RAD17 | Ser656 | SASELPAsQPQPFSA | phosphorylation unknown | 10608806 | SIGNOR-73524 |
| ATM | EIF4EBP1 | Ser112 | KRAGGEEsQFEMDI | phosphorylation down-regulates | 11146653 | SIGNOR-85619 |
| ATM | MECOM | Ser1037 | IGNSNHGsQSPRNVE | phosphorylation up-regulates activity | 29939287 | SIGNOR-273433 |
| ATM | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates quantity by stabilization | 17967874 | SIGNOR-158632 |
| ATM | PPP1R2 | Ser44 | DEELSKKsQKWDEMN | phosphorylation down-regulates | 18250156 | SIGNOR-160648 |
| ATM | ABRAXAS1 | Ser406 | GPGEYSRsPTF | phosphorylation up-regulates activity | 26778126 | SIGNOR-255588 |
| ATM | RAD50 | Ser635 | KLFDVCGsQDFESDL | phosphorylation unknown | 17570479 | SIGNOR-156077 |
| ATM | RANBP9 | – | phosphorylation up-regulates activity | 26943034 | SIGNOR-279005 | |
| ATM | CHEK2 | Ser28 | PHGSVTQsQGSSSQS | phosphorylation up-regulates activity | 10973490 | SIGNOR-81395 |
| ATM | MCM3 | Ser535 | ATDDPNFsQEDQQDT | phosphorylation unknown | 15210935 | SIGNOR-126308 |
| ATM | CHEK2 | Ser35 | SQGSSSQsQGISSSS | phosphorylation up-regulates activity | 10973490 | SIGNOR-81403 |
| ATM | USP28 | Ser495 | STSTESSsQDVESTF | phosphorylation down-regulates activity | 31938050 | SIGNOR-275854 |
| ATM | MACROD2 | – | phosphorylation down-regulates activity | 28069995 | SIGNOR-279792 | |
| ATM | RPA2 | Thr21 | YGGAGGYtQSPGGFG | phosphorylation up-regulates | 14872059 | SIGNOR-121861 |
| ATM | RBBP8 | Ser745 | SCLADSFsQAADEEE | phosphorylation down-regulates | 10910365 | SIGNOR-79876 |
| ATM | FANCD2 | Ser1404 | EEIKSQNsQESTADE | phosphorylation up-regulates | 12086603 | SIGNOR-90113 |
| ATM | CHEK1 | Ser317 | ENVKYSSsQPEPRTG | phosphorylation up-regulates | 20068082 | SIGNOR-163106 |
| ATM | SMURF2 | Ser384 | KILRQELsQQQPQAG | phosphorylation up-regulates activity | 33097595 | SIGNOR-277534 |
| ATM | CCDC6 | Thr434 | TPPPSPNtQTPVQPP | phosphorylation up-regulates | 23108047 | SIGNOR-199276 |
| ATM | USP10 | Ser337 | ASGTLPVsQPKSWAS | phosphorylation up-regulates quantity by stabilization | 20096447 | SIGNOR-276276 |
| ATM | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates quantity by stabilization | 20663147 | SIGNOR-167152 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | phosphorylation up-regulates → | AVEN PSer135 | phosphorylation up-regulates → | AVEN | 18571408 | SIGNOR-262636 |
| ATM | phosphorylation up-regulates → | XRCC6 PSer27 | phosphorylation up-regulates → | XRCC6 | 26337656 | SIGNOR-274020 |
| ATM | phosphorylation up-regulates → | USP28 PSer714 | phosphorylation down-regulates ⊣ | USP28 | 31938050 | SIGNOR-275853 |
| ATM | phosphorylation up-regulates → | HIF1A PSer696 | phosphorylation up-regulates → | HIF1A | 21095582 | SIGNOR-169999 |
| ATM | phosphorylation up-regulates → | TOP2B PSer1135 | phosphorylation down-regulates ⊣ | TOP2B | 32015321 | SIGNOR-277510 |
| ATM | phosphorylation up-regulates → | MDM4 PSer342 | phosphorylation down-regulates ⊣ | MDM4 | 16943424 | SIGNOR-149292 |
| ATM | phosphorylation up-regulates → | USP10 PThr42 | phosphorylation up-regulates → | USP10 | 35627217 | SIGNOR-279795 |
| ATM | phosphorylation up-regulates → | DCLRE1C PSer645 | phosphorylation up-regulates → | DCLRE1C | 16874298 | SIGNOR-148323 |
| ATM | phosphorylation up-regulates → | ATM PSer2996 | phosphorylation up-regulates → | ATM | 21149446 | SIGNOR-170473 |
| ATM | phosphorylation up-regulates → | ZFHX3 PSer1180 | phosphorylation up-regulates → | ZFHX3 | 21729327 | SIGNOR-279138 |
| ATM | phosphorylation up-regulates → | IKBKG PSer85 | phosphorylation down-regulates ⊣ | IKBKG | 16497931 | SIGNOR-144813 |
| ATM | phosphorylation up-regulates → | MDM2 PSer395 | phosphorylation down-regulates ⊣ | MDM2 | 11331603 | SIGNOR-107256 |
| ATM | phosphorylation up-regulates → | KHSRP PSer670 | phosphorylation up-regulates → | KHSRP | 21329876 | SIGNOR-172127 |
| ATM | phosphorylation up-regulates → | MDM2 PSer395 | phosphorylation down-regulates ⊣ | MDM2 | 17936559 | SIGNOR-158324 |
| ATM | phosphorylation up-regulates → | BRCA1 PSer1524 | phosphorylation up-regulates → | BRCA1 | 10550055 | SIGNOR-72068 |
| ATM | phosphorylation up-regulates → | AATF PSer189 | phosphorylation up-regulates → | AATF | 17157788 | SIGNOR-264415 |
| ATM | phosphorylation up-regulates → | ZNF148 PSer202 | phosphorylation up-regulates → | ZNF148 | 17560543 | SIGNOR-155634 |
| ATM | phosphorylation up-regulates → | TP53BP1 PSer1219 | phosphorylation up-regulates → | TP53BP1 | 22621922 | SIGNOR-197611 |
| ATM | phosphorylation up-regulates → | TP63 PSer560 | phosphorylation down-regulates ⊣ | TP63 | 18769144 | SIGNOR-180751 |
| ATM | phosphorylation up-regulates → | CHEK2 PSer33 | phosphorylation up-regulates → | CHEK2 | 10973490 | SIGNOR-81399 |
| ATM | phosphorylation up-regulates → | TP53 PSer9 | phosphorylation up-regulates → | TP53 | 11875057 | SIGNOR-115348 |
| ATM | phosphorylation up-regulates → | FANCD2 PSer1401 | phosphorylation up-regulates → | FANCD2 | 12086603 | SIGNOR-90109 |
| ATM | phosphorylation up-regulates → | MAD1L1 PSer214 | phosphorylation up-regulates → | MAD1L1 | 24728176 | SIGNOR-278467 |
| ATM | phosphorylation up-regulates → | DGCR8 PSer677 | phosphorylation up-regulates → | DGCR8 | 34188037 | SIGNOR-277307 |
| ATM | phosphorylation up-regulates → | MDM4 PSer367 | phosphorylation down-regulates ⊣ | MDM4 | 16943424 | SIGNOR-149296 |
| ATM | phosphorylation up-regulates → | SP1 PSer101 | phosphorylation down-regulates ⊣ | SP1 | 18619531 | SIGNOR-179435 |
| ATM | phosphorylation up-regulates → | USP28 PSer67 | phosphorylation down-regulates ⊣ | USP28 | 31938050 | SIGNOR-275852 |
| ATM | phosphorylation up-regulates → | PPM1G PSer183 | phosphorylation up-regulates → | PPM1G | 26324325 | SIGNOR-255591 |
| ATM | phosphorylation up-regulates → | TP53BP1 PSer29 | phosphorylation down-regulates ⊣ | TP53BP1 | 12697768 | SIGNOR-100645 |
| ATM | phosphorylation up-regulates → | BLM PThr99 | phosphorylation up-regulates → | BLM | 12034743 | SIGNOR-88010 |
| ATM | phosphorylation up-regulates → | DAXX PSer564 | phosphorylation down-regulates ⊣ | DAXX | 23405218 | SIGNOR-200889 |
| ATM | phosphorylation up-regulates → | BCL10 PThr91 | phosphorylation up-regulates → | BCL10 | 24732096 | SIGNOR-278392 |
| ATM | phosphorylation up-regulates → | FANCA PSer1449 | phosphorylation up-regulates → | FANCA | 19109555 | SIGNOR-182949 |
| ATM | phosphorylation up-regulates → | BRCA1 PSer1524 | phosphorylation down-regulates ⊣ | BRCA1 | 10550055 | SIGNOR-72079 |
| ATM | phosphorylation up-regulates → | METTL3 PSer43 | phosphorylation up-regulates → | METTL3 | 32615088 | SIGNOR-265969 |
| ATM | phosphorylation up-regulates → | NFAT5 PSer1247 | phosphorylation up-regulates → | NFAT5 | 15173573 | SIGNOR-125077 |
| ATM | phosphorylation up-regulates → | PAN2 PSer1003 | phosphorylation up-regulates → | PAN2 | 33097710 | SIGNOR-273508 |
| ATM | phosphorylation up-regulates → | NOP53 PSer233 | phosphorylation down-regulates ⊣ | NOP53 | 27829214 | SIGNOR-273506 |
| ATM | phosphorylation up-regulates → | XPA PSer196 | phosphorylation down-regulates ⊣ | XPA | 16540648 | SIGNOR-250580 |
| ATM | phosphorylation up-regulates → | FANCI PSer730 | phosphorylation down-regulates ⊣ | FANCI | 17412408 | SIGNOR-255590 |
| ATM | phosphorylation up-regulates → | DCLRE1C PSer503 | phosphorylation up-regulates → | DCLRE1C | 16874298 | SIGNOR-148315 |
| ATM | phosphorylation up-regulates → | TTC5 PSer203 | phosphorylation up-regulates → | TTC5 | 15448695 | SIGNOR-262645 |
| ATM | phosphorylation up-regulates → | TP53 PSer20 | phosphorylation up-regulates → | TP53 | 15254178 | SIGNOR-126757 |
| ATM | phosphorylation up-regulates → | E2F1 PSer31 | phosphorylation up-regulates → | E2F1 | 11459832 | SIGNOR-109416 |
| ATM | phosphorylation up-regulates → | NKX3-1 PThr166 | phosphorylation down-regulates ⊣ | NKX3-1 | 23890999 | SIGNOR-276500 |
| ATM | phosphorylation up-regulates → | BRCA1 PSer1423 | phosphorylation up-regulates → | BRCA1 | 10550055 | SIGNOR-72052 |
| ATM | phosphorylation up-regulates → | BUB1 PSer314 | phosphorylation up-regulates → | BUB1 | 22099307 | SIGNOR-177276 |
| ATM | phosphorylation up-regulates → | SNAI1 PSer100 | phosphorylation up-regulates → | SNAI1 | 23891091 | SIGNOR-279587 |
| ATM | phosphorylation up-regulates → | BRCA1 PSer1497 | phosphorylation up-regulates → | BRCA1 | 10550055 | SIGNOR-72064 |
| ATM | phosphorylation up-regulates → | RPA2 PThr21 | phosphorylation down-regulates ⊣ | RPA2 | 14872059 | SIGNOR-121865 |
| ATM | phosphorylation up-regulates → | EZH2 PSer729 | phosphorylation down-regulates ⊣ | EZH2 | 24162653 | SIGNOR-276602 |
| ATM | phosphorylation up-regulates → | DCK PSer74 | phosphorylation up-regulates → | DCK | 27879648 | SIGNOR-275798 |
| ATM | phosphorylation up-regulates → | POLL PThr204 | phosphorylation up-regulates → | POLL | 28109743 | SIGNOR-273510 |
| ATM | phosphorylation up-regulates → | BRCA1 PSer1542 | phosphorylation up-regulates → | BRCA1 | 10550055 | SIGNOR-72072 |
| ATM | phosphorylation up-regulates → | BRCA1 PSer1330 | phosphorylation up-regulates → | BRCA1 | 10550055 | SIGNOR-72048 |
| ATM | phosphorylation up-regulates → | CHEK2 PThr68 | phosphorylation up-regulates → | CHEK2 | 16481012 | SIGNOR-276053 |
| ATM | phosphorylation up-regulates → | KIFC1 PSer26 | phosphorylation up-regulates → | KIFC1 | 33397932 | SIGNOR-277295 |
| ATM | phosphorylation up-regulates → | MDM2 PSer429 | phosphorylation down-regulates ⊣ | MDM2 | 19816404 | SIGNOR-188412 |
| ATM | phosphorylation up-regulates → | BRCA1 PSer1497 | phosphorylation up-regulates → | BRCA1 | 19683496 | SIGNOR-187591 |
| ATM | phosphorylation up-regulates → | EZH2 PSer734 | phosphorylation down-regulates ⊣ | EZH2 | 24162653 | SIGNOR-279586 |
| ATM | phosphorylation up-regulates → | TERF1 PSer219 | phosphorylation up-regulates → | TERF1 | 11375976 | SIGNOR-108419 |
| ATM | phosphorylation up-regulates → | NBN PSer343 | phosphorylation up-regulates → | NBN | 10802669 | SIGNOR-77149 |
| ATM | phosphorylation up-regulates → | FBXO31 PSer278 | phosphorylation up-regulates → | FBXO31 | 19412162 | SIGNOR-185635 |
| ATM | phosphorylation up-regulates → | H2AX PSer140 | phosphorylation up-regulates → | H2AX | 18158901 | SIGNOR-160206 |
| ATM | phosphorylation up-regulates → | POLL PThr204 | phosphorylation up-regulates → | POLL | 28109743 | SIGNOR-273836 |
| ATM | phosphorylation up-regulates → | SMC1A PSer957 | phosphorylation up-regulates → | SMC1A | 11877377 | SIGNOR-115492 |
| ATM | phosphorylation up-regulates → | ATM PSer1981 | phosphorylation up-regulates → | ATM | 21149446 | SIGNOR-170469 |
| ATM | phosphorylation up-regulates → | ATF1 PSer51 | phosphorylation up-regulates → | ATF1 | 20730097 | SIGNOR-278909 |
| ATM | phosphorylation up-regulates → | CHEK1 PSer345 | phosphorylation up-regulates → | CHEK1 | 20068082 | SIGNOR-163110 |
| ATM | phosphorylation up-regulates → | WRN PSer1141 | phosphorylation down-regulates ⊣ | WRN | 10608806 | SIGNOR-250577 |
| ATM | phosphorylation up-regulates → | NABP2 PThr117 | phosphorylation up-regulates → | NABP2 | 18449195 | SIGNOR-262639 |
| ATM | phosphorylation up-regulates → | KHDC3L PThr156 | phosphorylation up-regulates → | KHDC3L | 31609975 | SIGNOR-273504 |
| ATM | phosphorylation up-regulates → | RELA PSer547 | phosphorylation down-regulates ⊣ | RELA | 24957606 | SIGNOR-279006 |
| ATM | phosphorylation up-regulates → | DCK PSer74 | phosphorylation up-regulates → | DCK | 22850745 | SIGNOR-278221 |
| ATM | phosphorylation up-regulates → | ATM PSer367 | phosphorylation up-regulates → | ATM | 21149446 | SIGNOR-170477 |
| ATM | phosphorylation up-regulates → | ITCH PSer162 | phosphorylation up-regulates → | ITCH | 23435430 | SIGNOR-276488 |
| ATM | phosphorylation up-regulates → | MECOM PSer1039 | phosphorylation up-regulates → | MECOM | 29939287 | SIGNOR-273434 |
| ATM | phosphorylation up-regulates → | ABL1 PSer446 | phosphorylation up-regulates → | ABL1 | 9168116 | SIGNOR-48818 |
| ATM | phosphorylation up-regulates → | NBN PSer278 | phosphorylation up-regulates → | NBN | 10839544 | SIGNOR-78025 |
| ATM | phosphorylation up-regulates → | NHEJ1 PSer251 | phosphorylation down-regulates ⊣ | NHEJ1 | 18644470 | SIGNOR-179528 |
| ATM | phosphorylation up-regulates → | USP10 PSer337 | phosphorylation up-regulates → | USP10 | 35627217 | SIGNOR-279796 |
| ATM | phosphorylation up-regulates → | XPA PSer173 | phosphorylation down-regulates ⊣ | XPA | 16540648 | SIGNOR-250579 |
| ATM | phosphorylation up-regulates → | CREB1 PThr100 | phosphorylation down-regulates ⊣ | CREB1 | 15073328 | SIGNOR-124051 |
| ATM | phosphorylation up-regulates → | ZEB1 PSer585 | phosphorylation up-regulates → | ZEB1 | 25086746 | SIGNOR-278329 |
| ATM | phosphorylation up-regulates → | TAOK1 PThr785 | phosphorylation up-regulates → | TAOK1 | 17396146 | SIGNOR-154175 |
| ATM | phosphorylation up-regulates → | MDM2 PSer395 | phosphorylation down-regulates ⊣ | MDM2 | 12383858 | SIGNOR-94268 |
| ATM | phosphorylation up-regulates → | TP53 PSer46 | phosphorylation up-regulates → | TP53 | 11875057 | SIGNOR-115344 |
| ATM | phosphorylation up-regulates → | KAT8 PThr392 | phosphorylation up-regulates → | KAT8 | 24953651 | SIGNOR-278350 |
| ATM | phosphorylation up-regulates → | WRAP53 PSer64 | phosphorylation up-regulates → | WRAP53 | 27715493 | SIGNOR-273511 |
| ATM | phosphorylation up-regulates → | XRCC6 PSer33 | phosphorylation up-regulates → | XRCC6 | 26337656 | SIGNOR-274021 |
| ATM | phosphorylation up-regulates → | NFAT5 PSer1367 | phosphorylation up-regulates → | NFAT5 | 15173573 | SIGNOR-125081 |
| ATM | phosphorylation up-regulates → | PNKP PSer114 | phosphorylation up-regulates → | PNKP | 21824916 | SIGNOR-176008 |
| ATM | phosphorylation up-regulates → | RAD9A PSer272 | phosphorylation up-regulates → | RAD9A | 11278446 | SIGNOR-105243 |
| ATM | phosphorylation up-regulates → | PRKDC PThr2609 | phosphorylation up-regulates → | PRKDC | 17189255 | SIGNOR-151441 |
| ATM | phosphorylation up-regulates → | UCHL3 PSer75 | phosphorylation up-regulates → | UCHL3 | 27941124 | SIGNOR-275910 |
| ATM | phosphorylation up-regulates → | FBXW7 PSer26 | phosphorylation up-regulates → | FBXW7 | 26774286 | SIGNOR-259942 |
| ATM | phosphorylation up-regulates → | NBN PSer615 | phosphorylation up-regulates → | NBN | 10839545 | SIGNOR-78034 |
| ATM | phosphorylation up-regulates → | RBBP8 PSer664 | phosphorylation down-regulates ⊣ | RBBP8 | 10910365 | SIGNOR-79872 |
| ATM | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 15254178 | SIGNOR-126753 |
| ATM | phosphorylation up-regulates → | KHDC3L PThr145 | phosphorylation up-regulates → | KHDC3L | 31609975 | SIGNOR-273505 |
| ATM | phosphorylation up-regulates → | TP63 PThr491 | phosphorylation down-regulates ⊣ | TP63 | 18769144 | SIGNOR-180755 |
| ATM | phosphorylation up-regulates → | PEX5 PSer141 | phosphorylation up-regulates → | PEX5 | 26344566 | SIGNOR-262792 |
| ATM | phosphorylation up-regulates → | ATM PSer440 | phosphorylation down-regulates ⊣ | ATM | 10608806 | SIGNOR-250576 |
| ATM | phosphorylation up-regulates → | ATM PSer1893 | phosphorylation up-regulates → | ATM | 21149446 | SIGNOR-170465 |
| ATM | phosphorylation up-regulates → | EP300 PSer106 | phosphorylation up-regulates → | EP300 | 20471956 | SIGNOR-165567 |
| ATM | phosphorylation up-regulates → | CDKN1B PSer140 | phosphorylation up-regulates → | CDKN1B | 27611996 | SIGNOR-279392 |
| ATM | phosphorylation up-regulates → | DYRK2 PThr106 | phosphorylation up-regulates → | DYRK2 | 19965871 | SIGNOR-275576 |
| ATM | phosphorylation up-regulates → | H2AX PSer140 | phosphorylation up-regulates → | H2AX | 21690091 | SIGNOR-174442 |
| ATM | phosphorylation up-regulates → | SIAH1 PSer19 | phosphorylation down-regulates ⊣ | SIAH1 | 18536714 | SIGNOR-177945 |
| ATM | phosphorylation up-regulates → | CHEK2 PSer50 | phosphorylation up-regulates → | CHEK2 | 10973490 | SIGNOR-81407 |
| ATM | phosphorylation up-regulates → | AGER PSer391 | phosphorylation up-regulates → | AGER | 28977635 | SIGNOR-278907 |
| ATM | phosphorylation up-regulates → | RNF40 PSer114 | phosphorylation up-regulates → | RNF40 | 21362549 | SIGNOR-276315 |
| ATM | phosphorylation up-regulates → | PRKAA2 PThr172 | phosphorylation up-regulates → | PRKAA2 | 23871434 | SIGNOR-275488 |
| ATM | phosphorylation up-regulates → | MRE11 PSer264 | phosphorylation up-regulates → | MRE11 | 10608806 | SIGNOR-73366 |
| ATM | phosphorylation up-regulates → | CCAR2 PThr454 | phosphorylation up-regulates → | CCAR2 | 22735644 | SIGNOR-267661 |
| ATM | phosphorylation up-regulates → | SMC1A PSer966 | phosphorylation up-regulates → | SMC1A | 11877377 | SIGNOR-115496 |
| ATM | phosphorylation up-regulates → | PNKP PSer126 | phosphorylation up-regulates → | PNKP | 21824916 | SIGNOR-176012 |
| ATM | phosphorylation up-regulates → | USP10 PThr42 | phosphorylation up-regulates → | USP10 | 20096447 | SIGNOR-276275 |
| ATM | phosphorylation up-regulates → | DYRK2 PSer442 | phosphorylation up-regulates → | DYRK2 | 19965871 | SIGNOR-275577 |
| ATM | phosphorylation up-regulates → | CHEK2 PThr68 | phosphorylation up-regulates → | CHEK2 | 10973490 | SIGNOR-81438 |
| ATM | phosphorylation up-regulates → | AVEN PSer308 | phosphorylation up-regulates → | AVEN | 18571408 | SIGNOR-262637 |
| ATM | phosphorylation up-regulates → | RNF20 PSer172 | phosphorylation up-regulates → | RNF20 | 21362549 | SIGNOR-276314 |
| ATM | phosphorylation up-regulates → | TP53 PSer20 | phosphorylation up-regulates → | TP53 | 20663147 | SIGNOR-167156 |
| ATM | phosphorylation up-regulates → | MDM4 PSer403 | phosphorylation down-regulates ⊣ | MDM4 | 16943424 | SIGNOR-149300 |
| ATM | phosphorylation up-regulates → | TP53BP1 PSer25 | phosphorylation down-regulates ⊣ | TP53BP1 | 12697768 | SIGNOR-100641 |
| ATM | phosphorylation up-regulates → | SMAD1 PSer239 | phosphorylation up-regulates → | SMAD1 | 22588298 | SIGNOR-197533 |
| ATM | phosphorylation up-regulates → | RNF138 PSer124 | phosphorylation up-regulates → | RNF138 | 27195665 | SIGNOR-279505 |
| ATM | phosphorylation up-regulates → | CHEK2 PSer19 | phosphorylation up-regulates → | CHEK2 | 10973490 | SIGNOR-81391 |
| ATM | phosphorylation up-regulates → | ABRAXAS1 PSer404 | phosphorylation up-regulates → | ABRAXAS1 | 26778126 | SIGNOR-255587 |
| ATM | phosphorylation up-regulates → | TP53BP1 PSer831 | phosphorylation up-regulates → | TP53BP1 | 22621922 | SIGNOR-197615 |
| ATM | phosphorylation up-regulates → | BRD7 PSer263 | phosphorylation down-regulates ⊣ | BRD7 | 33101843 | SIGNOR-279780 |
| ATM | phosphorylation up-regulates → | MPG PSer172 | phosphorylation up-regulates → | MPG | 25100205 | SIGNOR-279004 |
| ATM | phosphorylation up-regulates → | HNF1A PSer249 | phosphorylation up-regulates → | HNF1A | 24821553 | SIGNOR-205087 |
| ATM | phosphorylation up-regulates → | LARP7 PThr440 | phosphorylation down-regulates ⊣ | LARP7 | 32726637 | SIGNOR-275580 |
| ATM | phosphorylation up-regulates → | WRN PSer1292 | phosphorylation down-regulates ⊣ | WRN | 10608806 | SIGNOR-250578 |
| ATM | phosphorylation up-regulates → | DBF4 PThr449 | phosphorylation down-regulates ⊣ | DBF4 | 22123827 | SIGNOR-177801 |
| ATM | phosphorylation up-regulates → | CREB1 PSer107 | phosphorylation down-regulates ⊣ | CREB1 | 15073328 | SIGNOR-124047 |
| ATM | phosphorylation up-regulates → | STK11 PThr367 | phosphorylation up-regulates → | STK11 | 12234250 | SIGNOR-92873 |
| ATM | phosphorylation up-regulates → | ACTR8 PSer412 | phosphorylation down-regulates ⊣ | ACTR8 | 29759113 | SIGNOR-279437 |
| ATM | phosphorylation up-regulates → | ATF2 PSer498 | phosphorylation up-regulates → | ATF2 | 15916964 | SIGNOR-137623 |
| ATM | phosphorylation up-regulates → | TDP1 PSer81 | phosphorylation up-regulates → | TDP1 | 19851285 | SIGNOR-188772 |
| ATM | phosphorylation up-regulates → | ZNF420 PSer68 | phosphorylation down-regulates ⊣ | ZNF420 | 19377469 | SIGNOR-273513 |
| ATM | phosphorylation up-regulates → | TAOK1 PThr643 | phosphorylation up-regulates → | TAOK1 | 17396146 | SIGNOR-154171 |
| ATM | phosphorylation up-regulates → | UBQLN4 PSer318 | phosphorylation up-regulates → | UBQLN4 | 30612738 | SIGNOR-265076 |
| ATM | phosphorylation up-regulates → | MDM2 PSer386 | phosphorylation down-regulates ⊣ | MDM2 | 19816404 | SIGNOR-188408 |
| ATM | phosphorylation up-regulates → | SMC3 PSer1083 | phosphorylation down-regulates ⊣ | SMC3 | 18442975 | SIGNOR-178479 |
| ATM | phosphorylation up-regulates → | FANCD2 PSer222 | phosphorylation up-regulates → | FANCD2 | 12086603 | SIGNOR-90121 |
| ATM | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 11875057 | SIGNOR-115340 |
| ATM | phosphorylation up-regulates → | RRM2B PSer72 | phosphorylation up-regulates → | RRM2B | 19015526 | SIGNOR-182423 |
| ATM | phosphorylation up-regulates → | BTRC PSer158 | phosphorylation up-regulates → | BTRC | 33676897 | SIGNOR-277549 |
| ATM | phosphorylation up-regulates → | STK11 PThr363 | phosphorylation down-regulates ⊣ | STK11 | 12234250 | SIGNOR-92877 |
| ATM | phosphorylation up-regulates → | RAD17 PSer646 | phosphorylation down-regulates ⊣ | RAD17 | 10608806 | SIGNOR-73520 |
| ATM | phosphorylation up-regulates → | BRCA1 PSer1387 | phosphorylation up-regulates → | BRCA1 | 12183412 | SIGNOR-91482 |
| ATM | phosphorylation up-regulates → | PPP2R5C PSer520 | phosphorylation up-regulates → | PPP2R5C | 21460856 | SIGNOR-276318 |
| ATM | phosphorylation up-regulates → | BRCA1 PSer1457 | phosphorylation up-regulates → | BRCA1 | 10550055 | SIGNOR-72056 |
| ATM | phosphorylation up-regulates → | FANCD2 PSer1407 | phosphorylation up-regulates → | FANCD2 | 12086603 | SIGNOR-90117 |
| ATM | phosphorylation up-regulates → | PIDD1 PThr788 | phosphorylation up-regulates → | PIDD1 | 22854598 | SIGNOR-262640 |
| ATM | phosphorylation up-regulates → | BRCA1 PSer1466 | phosphorylation up-regulates → | BRCA1 | 10550055 | SIGNOR-72060 |
| ATM | phosphorylation up-regulates → | COP1 PSer387 | phosphorylation down-regulates ⊣ | COP1 | 16931761 | SIGNOR-149082 |
| ATM | phosphorylation up-regulates → | RASSF1 PSer135 | phosphorylation up-regulates → | RASSF1 | 19962312 | SIGNOR-161934 |
| ATM | phosphorylation up-regulates → | UFL1 PSer462 | phosphorylation up-regulates → | UFL1 | 30886146 | SIGNOR-265075 |
| ATM | phosphorylation up-regulates → | CREB1 PSer97 | phosphorylation down-regulates ⊣ | CREB1 | 15073328 | SIGNOR-124043 |
| ATM | phosphorylation up-regulates → | CHEK2 PThr26 | phosphorylation up-regulates → | CHEK2 | 12024051 | SIGNOR-87850 |
| ATM | phosphorylation up-regulates → | NOP53 PThr289 | phosphorylation down-regulates ⊣ | NOP53 | 27829214 | SIGNOR-273507 |
| ATM | phosphorylation up-regulates → | NBN PSer397 | phosphorylation up-regulates → | NBN | 10839545 | SIGNOR-78030 |
| ATM | phosphorylation up-regulates → | TAOK1 PSer990 | phosphorylation up-regulates → | TAOK1 | 17396146 | SIGNOR-154167 |
| ATM | phosphorylation up-regulates → | NKX3-1 PThr134 | phosphorylation down-regulates ⊣ | NKX3-1 | 23890999 | SIGNOR-276499 |
| ATM | phosphorylation up-regulates → | TP53BP1 PSer6 | phosphorylation down-regulates ⊣ | TP53BP1 | 12697768 | SIGNOR-100649 |
| ATM | phosphorylation up-regulates → | DBF4 PSer539 | phosphorylation down-regulates ⊣ | DBF4 | 22123827 | SIGNOR-177797 |
| ATM | phosphorylation up-regulates → | DCLRE1C PSer516 | phosphorylation up-regulates → | DCLRE1C | 16874298 | SIGNOR-148319 |
| ATM | phosphorylation up-regulates → | TP63 PSer477 | phosphorylation down-regulates ⊣ | TP63 | 18769144 | SIGNOR-180747 |
| ATM | phosphorylation up-regulates → | TP53BP1 PSer784 | phosphorylation down-regulates ⊣ | TP53BP1 | 12697768 | SIGNOR-100653 |
| ATM | phosphorylation up-regulates → | DBF4 PSer502 | phosphorylation down-regulates ⊣ | DBF4 | 22123827 | SIGNOR-177793 |
| ATM | phosphorylation up-regulates → | ATF2 PSer490 | phosphorylation up-regulates → | ATF2 | 15916964 | SIGNOR-137619 |
| ATM | phosphorylation up-regulates → | NBN PSer343 | phosphorylation up-regulates → | NBN | 10608806 | SIGNOR-73432 |
| ATM | phosphorylation up-regulates → | BUB3 PSer135 | phosphorylation up-regulates → | BUB3 | 35085551 | SIGNOR-277582 |
| ATM | phosphorylation up-regulates → | TP53 PSer20 | phosphorylation up-regulates → | TP53 | 17967874 | SIGNOR-158636 |
| ATM | phosphorylation up-regulates → | TP53BP1 PThr302 | phosphorylation up-regulates → | TP53BP1 | 22621922 | SIGNOR-197619 |
| ATM | phosphorylation up-regulates → | SMC1A PSer966 | phosphorylation up-regulates → | SMC1A | 11877376 | SIGNOR-255589 |
| ATM | phosphorylation up-regulates → | NFAT5 PSer1197 | phosphorylation up-regulates → | NFAT5 | 15173573 | SIGNOR-125073 |
| ATM | phosphorylation up-regulates → | KHSRP PSer274 | phosphorylation up-regulates → | KHSRP | 21329876 | SIGNOR-172123 |
| ATM | phosphorylation up-regulates → | RAD17 PSer656 | phosphorylation down-regulates ⊣ | RAD17 | 10608806 | SIGNOR-73524 |
| ATM | phosphorylation up-regulates → | EIF4EBP1 PSer112 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11146653 | SIGNOR-85619 |
| ATM | phosphorylation up-regulates → | MECOM PSer1037 | phosphorylation up-regulates → | MECOM | 29939287 | SIGNOR-273433 |
| ATM | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 17967874 | SIGNOR-158632 |
| ATM | phosphorylation up-regulates → | PPP1R2 PSer44 | phosphorylation down-regulates ⊣ | PPP1R2 | 18250156 | SIGNOR-160648 |
| ATM | phosphorylation up-regulates → | ABRAXAS1 PSer406 | phosphorylation up-regulates → | ABRAXAS1 | 26778126 | SIGNOR-255588 |
| ATM | phosphorylation up-regulates → | RAD50 PSer635 | phosphorylation down-regulates ⊣ | RAD50 | 17570479 | SIGNOR-156077 |
| ATM | phosphorylation up-regulates → | CHEK2 PSer28 | phosphorylation up-regulates → | CHEK2 | 10973490 | SIGNOR-81395 |
| ATM | phosphorylation up-regulates → | MCM3 PSer535 | phosphorylation down-regulates ⊣ | MCM3 | 15210935 | SIGNOR-126308 |
| ATM | phosphorylation up-regulates → | CHEK2 PSer35 | phosphorylation up-regulates → | CHEK2 | 10973490 | SIGNOR-81403 |
| ATM | phosphorylation up-regulates → | USP28 PSer495 | phosphorylation down-regulates ⊣ | USP28 | 31938050 | SIGNOR-275854 |
| ATM | phosphorylation up-regulates → | RPA2 PThr21 | phosphorylation up-regulates → | RPA2 | 14872059 | SIGNOR-121861 |
| ATM | phosphorylation up-regulates → | RBBP8 PSer745 | phosphorylation down-regulates ⊣ | RBBP8 | 10910365 | SIGNOR-79876 |
| ATM | phosphorylation up-regulates → | FANCD2 PSer1404 | phosphorylation up-regulates → | FANCD2 | 12086603 | SIGNOR-90113 |
| ATM | phosphorylation up-regulates → | CHEK1 PSer317 | phosphorylation up-regulates → | CHEK1 | 20068082 | SIGNOR-163106 |
| ATM | phosphorylation up-regulates → | SMURF2 PSer384 | phosphorylation up-regulates → | SMURF2 | 33097595 | SIGNOR-277534 |
| ATM | phosphorylation up-regulates → | CCDC6 PThr434 | phosphorylation up-regulates → | CCDC6 | 23108047 | SIGNOR-199276 |
| ATM | phosphorylation up-regulates → | USP10 PSer337 | phosphorylation up-regulates → | USP10 | 20096447 | SIGNOR-276276 |
| ATM | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 20663147 | SIGNOR-167152 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATM | phosphorylation → up-regulates activity | AVEN | SIGNOR-262636 |
| ATM | phosphorylation → up-regulates activity | XRCC6 | SIGNOR-274020 |
| ATM | phosphorylation down-regulates quantity by destabilization | UCK1 | SIGNOR-275963 |
| ATM | phosphorylation → down-regulates activity | USP28 | SIGNOR-275853 |
| ATM | phosphorylation → up-regulates | HIF1A | SIGNOR-169999 |
| ATM | phosphorylation down-regulates quantity by destabilization | TOP2B | SIGNOR-277510 |
| ATM | phosphorylation down-regulates | MDM4 | SIGNOR-149292 |
| ATM | phosphorylation → up-regulates activity | USP10 | SIGNOR-279795 |
| ATM | phosphorylation → up-regulates | DCLRE1C | SIGNOR-148323 |
| ATM | phosphorylation → up-regulates activity | ATM | SIGNOR-170473 |
| ATM | phosphorylation → up-regulates activity | ZFHX3 | SIGNOR-279138 |
| ATM | phosphorylation → down-regulates activity | IKBKG | SIGNOR-144813 |
| ATM | phosphorylation → down-regulates activity | MDM2 | SIGNOR-107256 |
| ATM | phosphorylation → up-regulates | KHSRP | SIGNOR-172127 |
| ATM | phosphorylation → down-regulates activity | MDM2 | SIGNOR-158324 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-72068 |
| ATM | phosphorylation → up-regulates quantity by stabilization | AATF | SIGNOR-264415 |
| ATM | phosphorylation → up-regulates | ZNF148 | SIGNOR-155634 |
| ATM | phosphorylation → up-regulates | TP53BP1 | SIGNOR-197611 |
| ATM | phosphorylation down-regulates | TP63 | SIGNOR-180751 |
| ATM | phosphorylation → up-regulates activity | CHEK2 | SIGNOR-81399 |
| ATM | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-115348 |
| ATM | phosphorylation → up-regulates | FANCD2 | SIGNOR-90109 |
| ATM | phosphorylation → up-regulates activity | MAD1L1 | SIGNOR-278467 |
| ATM | phosphorylation → down-regulates activity | BID | SIGNOR-279790 |
| ATM | phosphorylation → up-regulates quantity by stabilization | DGCR8 | SIGNOR-277307 |
| ATM | phosphorylation down-regulates quantity by destabilization | MDM4 | SIGNOR-149296 |
| ATM | phosphorylation → unknown | SP1 | SIGNOR-179435 |
| ATM | phosphorylation → down-regulates activity | USP28 | SIGNOR-275852 |
| ATM | phosphorylation → up-regulates activity | PPM1G | SIGNOR-255591 |
| ATM | phosphorylation → up-regulates activity | LAMTOR5 | SIGNOR-279791 |
| ATM | phosphorylation → unknown | TP53BP1 | SIGNOR-100645 |
| ATM | phosphorylation → up-regulates | BLM | SIGNOR-88010 |
| ATM | phosphorylation down-regulates | DAXX | SIGNOR-200889 |
| ATM | phosphorylation → up-regulates activity | HMGA1 | SIGNOR-279493 |
| ATM | phosphorylation → up-regulates activity | BCL10 | SIGNOR-278392 |
| ATM | phosphorylation → up-regulates | FANCA | SIGNOR-182949 |
| ATM | phosphorylation → unknown | BRCA1 | SIGNOR-72079 |
| ATM | phosphorylation → up-regulates | EXO1 | SIGNOR-162304 |
| ATM | phosphorylation → up-regulates activity | METTL3 | SIGNOR-265969 |
| ATM | phosphorylation → up-regulates | NFAT5 | SIGNOR-125077 |
| ATM | phosphorylation → up-regulates activity | PAN2 | SIGNOR-273508 |
| ATM | phosphorylation down-regulates quantity by destabilization | NOP53 | SIGNOR-273506 |
| ATM | phosphorylation → unknown | XPA | SIGNOR-250580 |
| ATM | phosphorylation → unknown | FANCI | SIGNOR-255590 |
| ATM | phosphorylation → up-regulates | DCLRE1C | SIGNOR-148315 |
| ATM | phosphorylation → up-regulates activity | TTC5 | SIGNOR-262645 |
| ATM | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-126757 |
| ATM | phosphorylation → down-regulates activity | ELF4 | SIGNOR-278466 |
| ATM | phosphorylation → up-regulates quantity by stabilization | E2F1 | SIGNOR-109416 |
| ATM | phosphorylation down-regulates quantity by destabilization | NKX3-1 | SIGNOR-276500 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-72052 |
| ATM | phosphorylation → up-regulates | BUB1 | SIGNOR-177276 |
| ATM | phosphorylation → up-regulates activity | SNAI1 | SIGNOR-279587 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-72064 |
| ATM | phosphorylation → unknown | RPA2 | SIGNOR-121865 |
| ATM | phosphorylation down-regulates quantity by destabilization | EZH2 | SIGNOR-276602 |
| ATM | phosphorylation → up-regulates activity | DCK | SIGNOR-275798 |
| ATM | phosphorylation → up-regulates activity | POLL | SIGNOR-273510 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-72072 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-72048 |
| ATM | phosphorylation → up-regulates activity | CHEK2 | SIGNOR-276053 |
| ATM | phosphorylation → up-regulates quantity by stabilization | KIFC1 | SIGNOR-277295 |
| ATM | phosphorylation → down-regulates activity | MDM2 | SIGNOR-188412 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-187591 |
| ATM | phosphorylation → down-regulates quantity | EZH2 | SIGNOR-279586 |
| ATM | phosphorylation → up-regulates activity | TERF1 | SIGNOR-108419 |
| ATM | phosphorylation → up-regulates | NBN | SIGNOR-77149 |
| ATM | phosphorylation → up-regulates | FBXO31 | SIGNOR-185635 |
| ATM | phosphorylation → up-regulates | H2AX | SIGNOR-160206 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-72075 |
| ATM | phosphorylation → up-regulates activity | POLL | SIGNOR-273836 |
| ATM | phosphorylation → up-regulates | SMC1A | SIGNOR-115492 |
| ATM | phosphorylation → up-regulates activity | ATM | SIGNOR-170469 |
| ATM | phosphorylation → up-regulates activity | ATF1 | SIGNOR-278909 |
| ATM | phosphorylation → up-regulates | CHEK1 | SIGNOR-163110 |
| ATM | phosphorylation → unknown | WRN | SIGNOR-250577 |
| ATM | phosphorylation → up-regulates activity | NABP2 | SIGNOR-262639 |
| ATM | phosphorylation → up-regulates activity | KHDC3L | SIGNOR-273504 |
| ATM | phosphorylation → up-regulates activity | APLF | SIGNOR-279492 |
| ATM | phosphorylation → down-regulates activity | RELA | SIGNOR-279006 |
| ATM | phosphorylation → up-regulates activity | DCK | SIGNOR-278221 |
| ATM | phosphorylation → up-regulates activity | ATM | SIGNOR-170477 |
| ATM | phosphorylation → up-regulates activity | ITCH | SIGNOR-276488 |
| ATM | phosphorylation → up-regulates activity | MECOM | SIGNOR-273434 |
| ATM | phosphorylation → up-regulates | ABL1 | SIGNOR-48818 |
| ATM | phosphorylation → up-regulates | NBN | SIGNOR-78025 |
| ATM | phosphorylation → unknown | NHEJ1 | SIGNOR-179528 |
| ATM | phosphorylation → up-regulates activity | USP10 | SIGNOR-279796 |
| ATM | phosphorylation → unknown | XPA | SIGNOR-250579 |
| ATM | phosphorylation → up-regulates | TAOK1 | SIGNOR-154178 |
| ATM | phosphorylation down-regulates | CREB1 | SIGNOR-124051 |
| ATM | phosphorylation → up-regulates activity | ZEB1 | SIGNOR-278329 |
| ATM | phosphorylation → up-regulates | TAOK1 | SIGNOR-154175 |
| ATM | phosphorylation → down-regulates activity | MDM2 | SIGNOR-94268 |
| ATM | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-115344 |
| ATM | phosphorylation → up-regulates activity | KAT8 | SIGNOR-278350 |
| ATM | phosphorylation → up-regulates activity | WRAP53 | SIGNOR-273511 |
| ATM | phosphorylation → up-regulates activity | XRCC6 | SIGNOR-274021 |
| ATM | phosphorylation → up-regulates | NFAT5 | SIGNOR-125081 |
| ATM | phosphorylation → up-regulates | PNKP | SIGNOR-176008 |
| ATM | phosphorylation → up-regulates activity | NPM1 | SIGNOR-280182 |
| ATM | phosphorylation → up-regulates activity | RAD9A | SIGNOR-105243 |
| ATM | phosphorylation → up-regulates | PRKDC | SIGNOR-151441 |
| ATM | phosphorylation → up-regulates activity | UCHL3 | SIGNOR-275910 |
| ATM | phosphorylation → up-regulates activity | FBXW7 | SIGNOR-259942 |
| ATM | phosphorylation → up-regulates | NBN | SIGNOR-78034 |
| ATM | phosphorylation down-regulates | RBBP8 | SIGNOR-79872 |
| ATM | phosphorylation → up-regulates | RNF20 | SIGNOR-174949 |
| ATM | phosphorylation → up-regulates activity | USP24 | SIGNOR-280043 |
| ATM | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-126753 |
| ATM | phosphorylation → up-regulates activity | KHDC3L | SIGNOR-273505 |
| ATM | phosphorylation down-regulates | TP63 | SIGNOR-180755 |
| ATM | phosphorylation → up-regulates activity | PEX5 | SIGNOR-262792 |
| ATM | phosphorylation → unknown | ATM | SIGNOR-250576 |
| ATM | phosphorylation → up-regulates activity | UCHL3 | SIGNOR-279794 |
| ATM | phosphorylation → up-regulates activity | PPP2R5D | SIGNOR-276319 |
| ATM | phosphorylation → up-regulates activity | ATM | SIGNOR-170465 |
| ATM | phosphorylation → up-regulates | EP300 | SIGNOR-165567 |
| ATM | phosphorylation → up-regulates quantity by stabilization | CDKN1B | SIGNOR-279392 |
| ATM | phosphorylation → up-regulates quantity by stabilization | DYRK2 | SIGNOR-275576 |
| ATM | phosphorylation → up-regulates | H2AX | SIGNOR-174442 |
| ATM | phosphorylation down-regulates | SIAH1 | SIGNOR-177945 |
| ATM | phosphorylation → up-regulates activity | PPP2R5C | SIGNOR-276320 |
| ATM | phosphorylation → up-regulates activity | CHEK2 | SIGNOR-81407 |
| ATM | phosphorylation → up-regulates activity | AGER | SIGNOR-278907 |
| ATM | phosphorylation → up-regulates | RNF40 | SIGNOR-175003 |
| ATM | phosphorylation → up-regulates activity | RNF40 | SIGNOR-276315 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-87845 |
| ATM | phosphorylation → up-regulates activity | PRKAA2 | SIGNOR-275488 |
| ATM | phosphorylation → up-regulates | MRE11 | SIGNOR-73366 |
| ATM | phosphorylation → up-regulates activity | CCAR2 | SIGNOR-267661 |
| ATM | phosphorylation → up-regulates activity | USP28 | SIGNOR-279007 |
| ATM | phosphorylation → up-regulates | SMC1A | SIGNOR-115496 |
| ATM | phosphorylation → up-regulates | PNKP | SIGNOR-176012 |
| ATM | phosphorylation → up-regulates quantity by stabilization | USP10 | SIGNOR-276275 |
| ATM | phosphorylation → up-regulates quantity by stabilization | DYRK2 | SIGNOR-275577 |
| ATM | phosphorylation → up-regulates activity | CHEK2 | SIGNOR-81438 |
| ATM | phosphorylation → up-regulates activity | AVEN | SIGNOR-262637 |
| ATM | phosphorylation → up-regulates activity | RNF20 | SIGNOR-276314 |
| ATM | phosphorylation → up-regulates | MDC1 | SIGNOR-98798 |
| ATM | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-167156 |
| ATM | phosphorylation down-regulates | MDM4 | SIGNOR-149300 |
| ATM | phosphorylation → unknown | TP53BP1 | SIGNOR-100641 |
| ATM | phosphorylation → up-regulates | SMAD1 | SIGNOR-197533 |
| ATM | phosphorylation → up-regulates activity | RNF138 | SIGNOR-279505 |
| ATM | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-151138 |
| ATM | phosphorylation → up-regulates activity | CHEK2 | SIGNOR-81391 |
| ATM | phosphorylation → up-regulates activity | ABRAXAS1 | SIGNOR-255587 |
| ATM | phosphorylation → up-regulates | TP53BP1 | SIGNOR-197615 |
| ATM | phosphorylation → down-regulates activity | BRD7 | SIGNOR-279780 |
| ATM | phosphorylation → up-regulates activity | MPG | SIGNOR-279004 |
| ATM | phosphorylation → up-regulates | HNF1A | SIGNOR-205087 |
| ATM | phosphorylation down-regulates quantity by destabilization | LARP7 | SIGNOR-275580 |
| ATM | phosphorylation → unknown | WRN | SIGNOR-250578 |
| ATM | phosphorylation down-regulates | MDM4 | SIGNOR-139403 |
| ATM | phosphorylation down-regulates | DBF4 | SIGNOR-177801 |
| ATM | phosphorylation down-regulates | CREB1 | SIGNOR-124047 |
| ATM | phosphorylation → up-regulates activity | L3MBTL2 | SIGNOR-266785 |
| ATM | phosphorylation → up-regulates | STK11 | SIGNOR-92873 |
| ATM | phosphorylation → down-regulates activity | ACTR8 | SIGNOR-279437 |
| ATM | phosphorylation → up-regulates | ATF2 | SIGNOR-137623 |
| ATM | phosphorylation → down-regulates quantity | NKX3-1 | SIGNOR-279726 |
| ATM | phosphorylation → up-regulates | TDP1 | SIGNOR-188772 |
| ATM | phosphorylation → down-regulates activity | ZNF420 | SIGNOR-273513 |
| ATM | phosphorylation → up-regulates | TAOK1 | SIGNOR-154171 |
| ATM | phosphorylation → down-regulates activity | PLK1 | SIGNOR-279793 |
| ATM | phosphorylation → up-regulates activity | UBQLN4 | SIGNOR-265076 |
| ATM | phosphorylation → down-regulates activity | MDM2 | SIGNOR-188408 |
| ATM | phosphorylation → unknown | SMC3 | SIGNOR-178479 |
| ATM | phosphorylation → up-regulates | FANCD2 | SIGNOR-90121 |
| ATM | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-115340 |
| ATM | phosphorylation → up-regulates | RRM2B | SIGNOR-182423 |
| ATM | phosphorylation → up-regulates activity | CSNK1D | SIGNOR-279504 |
| ATM | phosphorylation → up-regulates quantity by stabilization | BTRC | SIGNOR-277549 |
| ATM | phosphorylation → unknown | STK11 | SIGNOR-92877 |
| ATM | phosphorylation → unknown | RAD17 | SIGNOR-73520 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-91482 |
| ATM | phosphorylation → up-regulates activity | PPP2R5C | SIGNOR-276318 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-72056 |
| ATM | phosphorylation → up-regulates | FANCD2 | SIGNOR-90117 |
| ATM | phosphorylation → up-regulates activity | PIDD1 | SIGNOR-262640 |
| ATM | phosphorylation → up-regulates | BRCA1 | SIGNOR-72060 |
| ATM | phosphorylation down-regulates | COP1 | SIGNOR-149082 |
| ATM | phosphorylation → up-regulates | RASSF1 | SIGNOR-161934 |
| ATM | phosphorylation → up-regulates activity | UFL1 | SIGNOR-265075 |
| ATM | phosphorylation → down-regulates activity | CREB1 | SIGNOR-124043 |
| ATM | phosphorylation → up-regulates activity | CHEK2 | SIGNOR-87850 |
| ATM | phosphorylation → up-regulates activity | IPO9 | SIGNOR-278910 |
| ATM | phosphorylation down-regulates quantity by destabilization | NOP53 | SIGNOR-273507 |
| ATM | phosphorylation → up-regulates | NBN | SIGNOR-78030 |
| ATM | phosphorylation → up-regulates | TAOK1 | SIGNOR-154167 |
| ATM | phosphorylation down-regulates quantity by destabilization | NKX3-1 | SIGNOR-276499 |
| ATM | phosphorylation → unknown | TP53BP1 | SIGNOR-100649 |
| ATM | phosphorylation → up-regulates | TP53BP1 | SIGNOR-197622 |
| ATM | phosphorylation down-regulates | DBF4 | SIGNOR-177797 |
| ATM | phosphorylation → up-regulates | DCLRE1C | SIGNOR-148319 |
| ATM | phosphorylation down-regulates | TP63 | SIGNOR-180747 |
| ATM | phosphorylation → unknown | TP53BP1 | SIGNOR-100653 |
| ATM | phosphorylation down-regulates | DBF4 | SIGNOR-177793 |
| ATM | phosphorylation → up-regulates | ATF2 | SIGNOR-137619 |
| ATM | phosphorylation → up-regulates | NBN | SIGNOR-73432 |
| ATM | phosphorylation → up-regulates activity | BUB3 | SIGNOR-277582 |
| ATM | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-158636 |
| ATM | phosphorylation → up-regulates | TP53BP1 | SIGNOR-197619 |
| ATM | phosphorylation → up-regulates activity | SMC1A | SIGNOR-255589 |
| ATM | phosphorylation → up-regulates | NFAT5 | SIGNOR-125073 |
| ATM | phosphorylation → up-regulates | KHSRP | SIGNOR-172123 |
| ATM | phosphorylation → unknown | RAD17 | SIGNOR-73524 |
| ATM | phosphorylation down-regulates | EIF4EBP1 | SIGNOR-85619 |
| ATM | phosphorylation → up-regulates activity | MECOM | SIGNOR-273433 |
| ATM | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-158632 |
| ATM | phosphorylation down-regulates | PPP1R2 | SIGNOR-160648 |
| ATM | phosphorylation → up-regulates activity | ABRAXAS1 | SIGNOR-255588 |
| ATM | phosphorylation → unknown | RAD50 | SIGNOR-156077 |
| ATM | phosphorylation → up-regulates activity | RANBP9 | SIGNOR-279005 |
| ATM | phosphorylation → up-regulates activity | CHEK2 | SIGNOR-81395 |
| ATM | phosphorylation → unknown | MCM3 | SIGNOR-126308 |
| ATM | phosphorylation → up-regulates activity | CHEK2 | SIGNOR-81403 |
| ATM | phosphorylation → down-regulates activity | USP28 | SIGNOR-275854 |
| ATM | phosphorylation → down-regulates activity | MACROD2 | SIGNOR-279792 |
| ATM | phosphorylation → up-regulates | RPA2 | SIGNOR-121861 |
| ATM | phosphorylation down-regulates | RBBP8 | SIGNOR-79876 |
| ATM | phosphorylation → up-regulates | FANCD2 | SIGNOR-90113 |
| ATM | phosphorylation → up-regulates | CHEK1 | SIGNOR-163106 |
| ATM | phosphorylation → up-regulates activity | SMURF2 | SIGNOR-277534 |
| ATM | phosphorylation → up-regulates | CCDC6 | SIGNOR-199276 |
| ATM | phosphorylation → up-regulates quantity by stabilization | USP10 | SIGNOR-276276 |
| ATM | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-167152 |