| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK2 | CTBP1 | Ser422 | AHPPHAPsPGQTVKP | phosphorylation down-regulates | 15708980 | SIGNOR-134040 |
| MAPK8 | CTBP1 | Ser422 | AHPPHAPsPGQTVKP | phosphorylation down-regulates | 16984892 | SIGNOR-149721 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK2 | phosphorylation up-regulates → | CTBP1 PSer422 | phosphorylation down-regulates ⊣ | CTBP1 | 15708980 | SIGNOR-134040 |
| MAPK8 | phosphorylation up-regulates → | CTBP1 PSer422 | phosphorylation down-regulates ⊣ | CTBP1 | 16984892 | SIGNOR-149721 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| HIPK2 | phosphorylation![]() down-regulates | CTBP1 | SIGNOR-134040 |
| MAPK8 | phosphorylation![]() down-regulates | CTBP1 | SIGNOR-149721 |