| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AMPK | CTBP1 | Ser158 | REGTRVQsVEQIREV | phosphorylation down-regulates | 23291169 | SIGNOR-216604 |
| PAK1 | CTBP1 | Ser158 | REGTRVQsVEQIREV | phosphorylation down-regulates activity | 12872159 | SIGNOR-103943 |
| PRKAA1 | CTBP1 | Ser158 | REGTRVQsVEQIREV | phosphorylation down-regulates | 23291169 | SIGNOR-200250 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AMPK | phosphorylation up-regulates → | CTBP1 PSer158 | phosphorylation down-regulates ⊣ | CTBP1 | 23291169 | SIGNOR-216604 |
| PAK1 | phosphorylation up-regulates → | CTBP1 PSer158 | phosphorylation down-regulates ⊣ | CTBP1 | 12872159 | SIGNOR-103943 |
| PRKAA1 | phosphorylation up-regulates → | CTBP1 PSer158 | phosphorylation down-regulates ⊣ | CTBP1 | 23291169 | SIGNOR-200250 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AMPK | phosphorylation down-regulates | CTBP1 | SIGNOR-216604 |
| PAK1 | phosphorylation → down-regulates activity | CTBP1 | SIGNOR-103943 |
| PRKAA1 | phosphorylation down-regulates | CTBP1 | SIGNOR-200250 |
