| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | PDE3B | Ser295 | VIRPRRRsSCVSLGE | phosphorylation up-regulates | 10454575 | SIGNOR-70205 |
| AKT1 | PDE3B | Ser295 | VIRPRRRsSCVSLGE | phosphorylation up-regulates activity | 10454575 | SIGNOR-252573 |
| AKT | PDE3B | Ser295 | VIRPRRRsSCVSLGE | phosphorylation up-regulates activity | 10454575 | SIGNOR-251483 |
| AKT1 | PDE3B | Ser295 | VIRPRRRsSCVSLGE | phosphorylation up-regulates | 10454575 | SIGNOR-252583 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | phosphorylation up-regulates → | PDE3B PSer295 | phosphorylation up-regulates → | PDE3B | 10454575 | SIGNOR-70205 |
| AKT1 | phosphorylation up-regulates → | PDE3B PSer295 | phosphorylation up-regulates → | PDE3B | 10454575 | SIGNOR-252573 |
| AKT | phosphorylation up-regulates → | PDE3B PSer295 | phosphorylation up-regulates → | PDE3B | 10454575 | SIGNOR-251483 |
| AKT1 | phosphorylation up-regulates → | PDE3B PSer295 | phosphorylation up-regulates → | PDE3B | 10454575 | SIGNOR-252583 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT | phosphorylation → up-regulates | PDE3B | SIGNOR-70205 |
| AKT1 | phosphorylation → up-regulates activity | PDE3B | SIGNOR-252573 |
| AKT | phosphorylation → up-regulates activity | PDE3B | SIGNOR-251483 |
| AKT1 | phosphorylation → up-regulates | PDE3B | SIGNOR-252583 |
