Entity Details

Name	ORC2_Thr226
ID	Q13416
Role	residue
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Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CyclinA2/CDK2	ORC2	Thr226 View in OncoXplorer	SAPVGKEtPSKRMKR	phosphorylation up-regulates	11931757	SIGNOR-217308
CDK2	ORC2	Thr226 View in OncoXplorer	SAPVGKEtPSKRMKR	phosphorylation up-regulates	11931757	SIGNOR-116476
CDK2	ORC2	Thr226 View in OncoXplorer	SAPVGKEtPSKRMKR	phosphorylation up-regulates	22334659	SIGNOR-196048

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CyclinA2/CDK2	phosphorylation up-regulates →	ORC2 PThr226	phosphorylation up-regulates →	ORC2	11931757	SIGNOR-217308
CDK2	phosphorylation up-regulates →	ORC2 PThr226	phosphorylation up-regulates →	ORC2	11931757	SIGNOR-116476
CDK2	phosphorylation up-regulates →	ORC2 PThr226	phosphorylation up-regulates →	ORC2	22334659	SIGNOR-196048

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CyclinA2/CDK2	phosphorylation → up-regulates	ORC2	SIGNOR-217308
CDK2	phosphorylation → up-regulates	ORC2	SIGNOR-116476
CDK2	phosphorylation → up-regulates	ORC2	SIGNOR-196048