| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HCK | ADAM15 | Tyr715 | LVMLGASyWYRARLH | phosphorylation unknown | 11741929 | SIGNOR-112927 |
| LCK | ADAM15 | Tyr715 | LVMLGASyWYRARLH | phosphorylation up-regulates | 11741929 | SIGNOR-112931 |
| HCK | ADAM15 | Tyr715 | LVMLGASyWYRARLH | phosphorylation up-regulates | 11741929 | SIGNOR-112919 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HCK | phosphorylation up-regulates → | ADAM15 PTyr715 | phosphorylation down-regulates ⊣ | ADAM15 | 11741929 | SIGNOR-112927 |
| LCK | phosphorylation up-regulates → | ADAM15 PTyr715 | phosphorylation up-regulates → | ADAM15 | 11741929 | SIGNOR-112931 |
| HCK | phosphorylation up-regulates → | ADAM15 PTyr715 | phosphorylation up-regulates → | ADAM15 | 11741929 | SIGNOR-112919 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| HCK | phosphorylation → unknown | ADAM15 | SIGNOR-112927 |
| LCK | phosphorylation → up-regulates | ADAM15 | SIGNOR-112931 |
| HCK | phosphorylation → up-regulates | ADAM15 | SIGNOR-112919 |
