| Name | ROCK1 |
| ID | Q13464 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 76-338 PROSITE-ProRule
AGC-kinase C-terminal 341-409 PROSITE-ProRule
REM-1 479-556 PROSITE-ProRule
RhoBD 949-1015 PROSITE-ProRule
PH 1118-1317 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ROCK1 | ADD1 | Thr445 | QKQQREKtRWLNSGR | phosphorylation up-regulates | 10209029 | SIGNOR-66992 |
| ROCK1 | MYL9 | Thr19 | KKRPQRAtSNVFAMF | phosphorylation up-regulates activity | 21457715 | SIGNOR-260308 |
| ROCK1 | ARHGAP35 | Thr1226 | LRSLRRNtKKPKPKP | phosphorylation down-regulates activity | 19103606 | SIGNOR-276178 |
| ROCK1 | ARHGAP24 | Ser574 | NSNSCRSsTTTCPEQ | phosphorylation up-regulates activity | 16862148 | SIGNOR-249303 |
| ROCK1 | ARHGAP24 | Thr577 | SCRSSTTtCPEQDFF | phosphorylation up-regulates activity | 16862148 | SIGNOR-249301 |
| ROCK1 | SMAD5 | – | phosphorylation up-regulates activity | 34285210 | SIGNOR-280107 | |
| ROCK1 | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates quantity | 33297931 | SIGNOR-280108 |
| ROCK1 | MSN | Thr558 | LGRDKYKtLRQIRQG | phosphorylation up-regulates activity | 9856983 | SIGNOR-249014 |
| ROCK1 | LIMK2 | Thr526 | NGKSYDEtVDIFSFG | phosphorylation up-regulates activity | 11018042 | SIGNOR-249053 |
| ROCK1 | BECN1 | Thr119 | LSRRLKVtGDLFDIM | phosphorylation up-regulates activity | 23877263 | SIGNOR-278198 |
| ROCK1 | MYL12A | Ser19 | KRPQRATsNVFAMFD | phosphorylation up-regulates activity | 12185584 | SIGNOR-263073 |
| ROCK1 | FHOD1 | Ser1137 | RSRGNRKsLRRTLKS | phosphorylation up-regulates | 18239683 | SIGNOR-160548 |
| ROCK1 | DES | Thr17 | RVSSYRRtFGGAPGF | phosphorylation down-regulates | 12686604 | SIGNOR-100177 |
| ROCK1 | PPP1R12A | Thr696 | ARQSRRStQGVTLTD | phosphorylation down-regulates | 8662509 | SIGNOR-42354 |
| ROCK1 | SLC9A1 | – | phosphorylation up-regulates activity | 27302366 | SIGNOR-279566 | |
| ROCK1 | DES | Thr77 | RASRLGTtRTPSSYG | phosphorylation unknown | 10574968 | SIGNOR-249033 |
| ROCK1 | FHOD3 | – | phosphorylation up-regulates activity | 23052206 | SIGNOR-278903 | |
| ROCK1 | EZR | Thr567 | QGRDKYKtLRQIRQG | phosphorylation up-regulates | 19386264 | SIGNOR-185567 |
| ROCK1 | SOX9 | Ser181 | YQPRRRKsVKNGQAE | phosphorylation up-regulates | 20039424 | SIGNOR-162643 |
| ROCK1 | ARHGAP24 | Ser402 | LSGSKTNsPKNSVHK | phosphorylation up-regulates activity | 16862148 | SIGNOR-249304 |
| ROCK1 | KCNK3 | Ser393 | GLMKRRSsV | phosphorylation up-regulates activity | 21838752 | SIGNOR-176029 |
| ROCK1 | PPP1R12B | Thr646 | ARQTRRStQGVTLTD | phosphorylation down-regulates | 22937917 | SIGNOR-198812 |
| ROCK1 | ARHGAP35 | Ser1236 | PKPKPRPsITKATWE | phosphorylation down-regulates activity | 19103606 | SIGNOR-276176 |
| ROCK1 | PFN1 | Ser138 | MASHLRRsQY | phosphorylation down-regulates | 22479341 | SIGNOR-196820 |
| ROCK1 | KCNK3 | Ser336 | IPRDLSTsDTCVEQS | phosphorylation down-regulates | 21838752 | SIGNOR-176025 |
| ROCK1 | ARHGAP24 | Ser413 | SVHKLDVsRSPPLMV | phosphorylation up-regulates activity | 16862148 | SIGNOR-249306 |
| ROCK1 | MYL12B | Thr19 | KKRPQRAtSNVFAMF | phosphorylation up-regulates | 12185584 | SIGNOR-91546 |
| ROCK1 | PTEN | Ser229 | VKIYSSNsGPTRRED | phosphorylation up-regulates | 15793569 | SIGNOR-134851 |
| ROCK1 | GFAP | Ser13 | ITSAARRsYVSSGEM | phosphorylation down-regulates activity | 12686604 | SIGNOR-100181 |
| ROCK1 | FHOD1 | Ser1131 | AARERKRsRGNRKSL | phosphorylation up-regulates | 18239683 | SIGNOR-160544 |
| ROCK1 | ARHGAP24 | Thr452 | GLEKTQTtPNGSLQA | phosphorylation up-regulates activity | 16862148 | SIGNOR-249310 |
| ROCK1 | ARHGAP35 | Ser1150 | LERGRKVsIVSKPVL | phosphorylation down-regulates activity | 19103606 | SIGNOR-276177 |
| ROCK1 | LIMK2 | Thr505 | NDRKKRYtVVGNPYW | phosphorylation up-regulates | 11018042 | SIGNOR-82755 |
| ROCK1 | MYL12A | Thr18 | KKRPQRAtSNVFAMF | phosphorylation up-regulates activity | 12185584 | SIGNOR-263074 |
| ROCK1 | MAPK8IP3 | Ser364 | TRLDRTGsSPTQGIV | phosphorylation up-regulates | 15767678 | SIGNOR-134584 |
| ROCK1 | ARHGAP24 | Ser573 | ENSNSCRsSTTTCPE | phosphorylation up-regulates activity | 16862148 | SIGNOR-249302 |
| ROCK1 | MYL9 | Ser20 | KRPQRATsNVFAMFD | phosphorylation up-regulates | 8702756 | SIGNOR-43031 |
| ROCK1 | ARHGAP24 | Ser415 | HKLDVSRsPPLMVKK | phosphorylation up-regulates activity | 16862148 | SIGNOR-249307 |
| ROCK1 | VIM | Ser72 | SSAVRLRsSVPGVRL | phosphorylation down-regulates activity | 9565595 | SIGNOR-248998 |
| ROCK1 | DES | Thr76 | LRASRLGtTRTPSSY | phosphorylation unknown | 10574968 | SIGNOR-249031 |
| ROCK1 | ARHGAP24 | Thr576 | NSCRSSTtTCPEQDF | phosphorylation up-regulates activity | 16862148 | SIGNOR-249300 |
| ROCK1 | RDX | Thr573 | RQIRQGNtKQRIDEF | phosphorylation unknown | 9456324 | SIGNOR-248995 |
| ROCK1 | PDPK1 | – | phosphorylation up-regulates activity | 26241960 | SIGNOR-279758 | |
| ROCK1 | GFAP | Thr7 | tSAARRSY | phosphorylation down-regulates activity | 12686604 | SIGNOR-100192 |
| ROCK1 | ARHGAP35 | Ser1236 | PKPKPRPsITKATWE | phosphorylation down-regulates | 19103606 | SIGNOR-182853 |
| ROCK1 | LIMK1 | Thr508 | PDRKKRYtVVGNPYW | phosphorylation up-regulates activity | 10652353 | SIGNOR-74569 |
| ROCK1 | DAPK3 | – | phosphorylation up-regulates activity | 25723491 | SIGNOR-279102 | |
| ROCK1 | MAPK8IP3 | Ser314 | RAREKRDsRNMEVQV | phosphorylation up-regulates | 15767678 | SIGNOR-134580 |
| ROCK1 | PPP1R12A | Thr853 | PREKRRStGVSFWTQ | phosphorylation down-regulates activity | 10601309 | SIGNOR-249034 |
| ROCK1 | RND3 | Ser11 | RRASQKLsSKSIMDP | phosphorylation up-regulates | 15775972 | SIGNOR-134703 |
| ROCK1 | DNM1L | Ser637 | VPVARKLsAREQRDC | phosphorylation up-regulates activity | 31063459 | SIGNOR-262549 |
| ROCK1 | FHOD1 | Thr1141 | NRKSLRRtLKSGLGD | phosphorylation up-regulates | 18239683 | SIGNOR-160552 |
| ROCK1 | ARHGAP24 | Thr575 | SNSCRSStTTCPEQD | phosphorylation up-regulates activity | 16862148 | SIGNOR-249299 |
| ROCK1 | MAPK8IP3 | Ser365 | RLDRTGSsPTQGIVN | phosphorylation up-regulates | 15767678 | SIGNOR-134588 |
| ROCK1 | ADD1 | Thr480 | TKEDGHRtSTSAVPN | phosphorylation up-regulates | 10209029 | SIGNOR-66996 |
| ROCK1 | RDX | Thr564 | AGRDKYKtLRQIRQG | phosphorylation up-regulates activity | 9456324 | SIGNOR-248994 |
| ROCK1 | MAPK8 | – | phosphorylation up-regulates activity | 15068801 | SIGNOR-123717 | |
| ROCK1 | ARHGAP24 | Ser437 | SGIVTNGsFSSSNAE | phosphorylation up-regulates activity | 16862148 | SIGNOR-249305 |
| ROCK1 | MPRIP | – | phosphorylation down-regulates | 17761936 | SIGNOR-157593 | |
| ROCK1 | GFAP | Ser38 | LGPGTRLsLARMPPP | phosphorylation down-regulates activity | 12686604 | SIGNOR-100188 |
| ROCK1 | MYL12B | Ser20 | KRPQRATsNVFAMFD | phosphorylation up-regulates | 12185584 | SIGNOR-91542 |
| ROCK1 | PTEN | Thr232 | YSSNSGPtRREDKFM | phosphorylation up-regulates | 15793569 | SIGNOR-134855 |
| ROCK1 | ARHGAP24 | – | phosphorylation up-regulates | 16862148 | SIGNOR-148262 | |
| ROCK1 | MYL9 | Ser20 | KRPQRATsNVFAMFD | phosphorylation up-regulates activity | 21457715 | SIGNOR-260307 |
| ROCK1 | DPYSL2 | Thr555 | DNIPRRTtQRIVAPP | phosphorylation unknown | 10818093 | SIGNOR-249042 |
| ROCK1 | DES | Thr17 | RVSSYRRtFGGAPGF | phosphorylation unknown | 10574968 | SIGNOR-249032 |
| ROCK1 | ARHGAP35 | Ser1150 | LERGRKVsIVSKPVL | phosphorylation down-regulates | 19103606 | SIGNOR-182849 |
| ROCK1 | ARHGAP24 | Ser391 | RSSMNNGsPTALSGS | phosphorylation up-regulates activity | 16862148 | SIGNOR-249309 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ROCK1 | phosphorylation up-regulates → | ADD1 PThr445 | phosphorylation up-regulates → | ADD1 | 10209029 | SIGNOR-66992 |
| ROCK1 | phosphorylation up-regulates → | MYL9 PThr19 | phosphorylation up-regulates → | MYL9 | 21457715 | SIGNOR-260308 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP35 PThr1226 | phosphorylation down-regulates ⊣ | ARHGAP35 | 19103606 | SIGNOR-276178 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PSer574 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249303 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PThr577 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249301 |
| ROCK1 | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 33297931 | SIGNOR-280108 |
| ROCK1 | phosphorylation up-regulates → | MSN PThr558 | phosphorylation up-regulates → | MSN | 9856983 | SIGNOR-249014 |
| ROCK1 | phosphorylation up-regulates → | LIMK2 PThr526 | phosphorylation up-regulates → | LIMK2 | 11018042 | SIGNOR-249053 |
| ROCK1 | phosphorylation up-regulates → | BECN1 PThr119 | phosphorylation up-regulates → | BECN1 | 23877263 | SIGNOR-278198 |
| ROCK1 | phosphorylation up-regulates → | MYL12A PSer19 | phosphorylation up-regulates → | MYL12A | 12185584 | SIGNOR-263073 |
| ROCK1 | phosphorylation up-regulates → | FHOD1 PSer1137 | phosphorylation up-regulates → | FHOD1 | 18239683 | SIGNOR-160548 |
| ROCK1 | phosphorylation up-regulates → | DES PThr17 | phosphorylation down-regulates ⊣ | DES | 12686604 | SIGNOR-100177 |
| ROCK1 | phosphorylation up-regulates → | PPP1R12A PThr696 | phosphorylation down-regulates ⊣ | PPP1R12A | 8662509 | SIGNOR-42354 |
| ROCK1 | phosphorylation up-regulates → | DES PThr77 | phosphorylation down-regulates ⊣ | DES | 10574968 | SIGNOR-249033 |
| ROCK1 | phosphorylation up-regulates → | EZR PThr567 | phosphorylation up-regulates → | EZR | 19386264 | SIGNOR-185567 |
| ROCK1 | phosphorylation up-regulates → | SOX9 PSer181 | phosphorylation up-regulates → | SOX9 | 20039424 | SIGNOR-162643 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PSer402 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249304 |
| ROCK1 | phosphorylation up-regulates → | KCNK3 PSer393 | phosphorylation up-regulates → | KCNK3 | 21838752 | SIGNOR-176029 |
| ROCK1 | phosphorylation up-regulates → | PPP1R12B PThr646 | phosphorylation down-regulates ⊣ | PPP1R12B | 22937917 | SIGNOR-198812 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP35 PSer1236 | phosphorylation down-regulates ⊣ | ARHGAP35 | 19103606 | SIGNOR-276176 |
| ROCK1 | phosphorylation up-regulates → | PFN1 PSer138 | phosphorylation down-regulates ⊣ | PFN1 | 22479341 | SIGNOR-196820 |
| ROCK1 | phosphorylation up-regulates → | KCNK3 PSer336 | phosphorylation down-regulates ⊣ | KCNK3 | 21838752 | SIGNOR-176025 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PSer413 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249306 |
| ROCK1 | phosphorylation up-regulates → | MYL12B PThr19 | phosphorylation up-regulates → | MYL12B | 12185584 | SIGNOR-91546 |
| ROCK1 | phosphorylation up-regulates → | PTEN PSer229 | phosphorylation up-regulates → | PTEN | 15793569 | SIGNOR-134851 |
| ROCK1 | phosphorylation up-regulates → | GFAP PSer13 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100181 |
| ROCK1 | phosphorylation up-regulates → | FHOD1 PSer1131 | phosphorylation up-regulates → | FHOD1 | 18239683 | SIGNOR-160544 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PThr452 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249310 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP35 PSer1150 | phosphorylation down-regulates ⊣ | ARHGAP35 | 19103606 | SIGNOR-276177 |
| ROCK1 | phosphorylation up-regulates → | LIMK2 PThr505 | phosphorylation up-regulates → | LIMK2 | 11018042 | SIGNOR-82755 |
| ROCK1 | phosphorylation up-regulates → | MYL12A PThr18 | phosphorylation up-regulates → | MYL12A | 12185584 | SIGNOR-263074 |
| ROCK1 | phosphorylation up-regulates → | MAPK8IP3 PSer364 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134584 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PSer573 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249302 |
| ROCK1 | phosphorylation up-regulates → | MYL9 PSer20 | phosphorylation up-regulates → | MYL9 | 8702756 | SIGNOR-43031 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PSer415 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249307 |
| ROCK1 | phosphorylation up-regulates → | VIM PSer72 | phosphorylation down-regulates ⊣ | VIM | 9565595 | SIGNOR-248998 |
| ROCK1 | phosphorylation up-regulates → | DES PThr76 | phosphorylation down-regulates ⊣ | DES | 10574968 | SIGNOR-249031 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PThr576 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249300 |
| ROCK1 | phosphorylation up-regulates → | RDX PThr573 | phosphorylation down-regulates ⊣ | RDX | 9456324 | SIGNOR-248995 |
| ROCK1 | phosphorylation up-regulates → | GFAP PThr7 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100192 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP35 PSer1236 | phosphorylation down-regulates ⊣ | ARHGAP35 | 19103606 | SIGNOR-182853 |
| ROCK1 | phosphorylation up-regulates → | LIMK1 PThr508 | phosphorylation up-regulates → | LIMK1 | 10652353 | SIGNOR-74569 |
| ROCK1 | phosphorylation up-regulates → | MAPK8IP3 PSer314 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134580 |
| ROCK1 | phosphorylation up-regulates → | PPP1R12A PThr853 | phosphorylation down-regulates ⊣ | PPP1R12A | 10601309 | SIGNOR-249034 |
| ROCK1 | phosphorylation up-regulates → | RND3 PSer11 | phosphorylation up-regulates → | RND3 | 15775972 | SIGNOR-134703 |
| ROCK1 | phosphorylation up-regulates → | DNM1L PSer637 | phosphorylation up-regulates → | DNM1L | 31063459 | SIGNOR-262549 |
| ROCK1 | phosphorylation up-regulates → | FHOD1 PThr1141 | phosphorylation up-regulates → | FHOD1 | 18239683 | SIGNOR-160552 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PThr575 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249299 |
| ROCK1 | phosphorylation up-regulates → | MAPK8IP3 PSer365 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134588 |
| ROCK1 | phosphorylation up-regulates → | ADD1 PThr480 | phosphorylation up-regulates → | ADD1 | 10209029 | SIGNOR-66996 |
| ROCK1 | phosphorylation up-regulates → | RDX PThr564 | phosphorylation up-regulates → | RDX | 9456324 | SIGNOR-248994 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PSer437 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249305 |
| ROCK1 | phosphorylation up-regulates → | GFAP PSer38 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100188 |
| ROCK1 | phosphorylation up-regulates → | MYL12B PSer20 | phosphorylation up-regulates → | MYL12B | 12185584 | SIGNOR-91542 |
| ROCK1 | phosphorylation up-regulates → | PTEN PThr232 | phosphorylation up-regulates → | PTEN | 15793569 | SIGNOR-134855 |
| ROCK1 | phosphorylation up-regulates → | MYL9 PSer20 | phosphorylation up-regulates → | MYL9 | 21457715 | SIGNOR-260307 |
| ROCK1 | phosphorylation up-regulates → | DPYSL2 PThr555 | phosphorylation down-regulates ⊣ | DPYSL2 | 10818093 | SIGNOR-249042 |
| ROCK1 | phosphorylation up-regulates → | DES PThr17 | phosphorylation down-regulates ⊣ | DES | 10574968 | SIGNOR-249032 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP35 PSer1150 | phosphorylation down-regulates ⊣ | ARHGAP35 | 19103606 | SIGNOR-182849 |
| ROCK1 | phosphorylation up-regulates → | ARHGAP24 PSer391 | phosphorylation up-regulates → | ARHGAP24 | 16862148 | SIGNOR-249309 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ROCK1 | phosphorylation → up-regulates | ADD1 | SIGNOR-66992 |
| ROCK1 | phosphorylation → up-regulates activity | MYL9 | SIGNOR-260308 |
| ROCK1 | phosphorylation → down-regulates activity | ARHGAP35 | SIGNOR-276178 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249303 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249301 |
| ROCK1 | phosphorylation → up-regulates activity | SMAD5 | SIGNOR-280107 |
| ROCK1 | phosphorylation → up-regulates quantity | TP53 | SIGNOR-280108 |
| ROCK1 | phosphorylation → up-regulates activity | MSN | SIGNOR-249014 |
| ROCK1 | phosphorylation → up-regulates activity | LIMK2 | SIGNOR-249053 |
| ROCK1 | phosphorylation → up-regulates activity | BECN1 | SIGNOR-278198 |
| ROCK1 | phosphorylation → up-regulates activity | MYL12A | SIGNOR-263073 |
| ROCK1 | phosphorylation → up-regulates | FHOD1 | SIGNOR-160548 |
| ROCK1 | phosphorylation down-regulates | DES | SIGNOR-100177 |
| ROCK1 | phosphorylation down-regulates | PPP1R12A | SIGNOR-42354 |
| ROCK1 | phosphorylation → up-regulates activity | SLC9A1 | SIGNOR-279566 |
| ROCK1 | phosphorylation → unknown | DES | SIGNOR-249033 |
| ROCK1 | phosphorylation → up-regulates activity | FHOD3 | SIGNOR-278903 |
| ROCK1 | phosphorylation → up-regulates | EZR | SIGNOR-185567 |
| ROCK1 | phosphorylation → up-regulates | SOX9 | SIGNOR-162643 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249304 |
| ROCK1 | phosphorylation → up-regulates activity | KCNK3 | SIGNOR-176029 |
| ROCK1 | phosphorylation down-regulates | PPP1R12B | SIGNOR-198812 |
| ROCK1 | phosphorylation → down-regulates activity | ARHGAP35 | SIGNOR-276176 |
| ROCK1 | phosphorylation down-regulates | PFN1 | SIGNOR-196820 |
| ROCK1 | phosphorylation down-regulates | KCNK3 | SIGNOR-176025 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249306 |
| ROCK1 | phosphorylation → up-regulates | MYL12B | SIGNOR-91546 |
| ROCK1 | phosphorylation → up-regulates | PTEN | SIGNOR-134851 |
| ROCK1 | phosphorylation → down-regulates activity | GFAP | SIGNOR-100181 |
| ROCK1 | phosphorylation → up-regulates | FHOD1 | SIGNOR-160544 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249310 |
| ROCK1 | phosphorylation → down-regulates activity | ARHGAP35 | SIGNOR-276177 |
| ROCK1 | phosphorylation → up-regulates | LIMK2 | SIGNOR-82755 |
| ROCK1 | phosphorylation → up-regulates activity | MYL12A | SIGNOR-263074 |
| ROCK1 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134584 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249302 |
| ROCK1 | phosphorylation → up-regulates | MYL9 | SIGNOR-43031 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249307 |
| ROCK1 | phosphorylation → down-regulates activity | VIM | SIGNOR-248998 |
| ROCK1 | phosphorylation → unknown | DES | SIGNOR-249031 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249300 |
| ROCK1 | phosphorylation → unknown | RDX | SIGNOR-248995 |
| ROCK1 | phosphorylation → up-regulates activity | PDPK1 | SIGNOR-279758 |
| ROCK1 | phosphorylation → down-regulates activity | GFAP | SIGNOR-100192 |
| ROCK1 | phosphorylation down-regulates | ARHGAP35 | SIGNOR-182853 |
| ROCK1 | phosphorylation → up-regulates activity | LIMK1 | SIGNOR-74569 |
| ROCK1 | phosphorylation → up-regulates activity | DAPK3 | SIGNOR-279102 |
| ROCK1 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134580 |
| ROCK1 | phosphorylation → down-regulates activity | PPP1R12A | SIGNOR-249034 |
| ROCK1 | phosphorylation → up-regulates | RND3 | SIGNOR-134703 |
| ROCK1 | phosphorylation → up-regulates activity | DNM1L | SIGNOR-262549 |
| ROCK1 | phosphorylation → up-regulates | FHOD1 | SIGNOR-160552 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249299 |
| ROCK1 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134588 |
| ROCK1 | phosphorylation → up-regulates | ADD1 | SIGNOR-66996 |
| ROCK1 | phosphorylation → up-regulates activity | RDX | SIGNOR-248994 |
| ROCK1 | phosphorylation → up-regulates activity | MAPK8 | SIGNOR-123717 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249305 |
| ROCK1 | phosphorylation down-regulates | MPRIP | SIGNOR-157593 |
| ROCK1 | phosphorylation → down-regulates activity | GFAP | SIGNOR-100188 |
| ROCK1 | phosphorylation → up-regulates | MYL12B | SIGNOR-91542 |
| ROCK1 | phosphorylation → up-regulates | PTEN | SIGNOR-134855 |
| ROCK1 | phosphorylation → up-regulates | ARHGAP24 | SIGNOR-148262 |
| ROCK1 | phosphorylation → up-regulates activity | MYL9 | SIGNOR-260307 |
| ROCK1 | phosphorylation → unknown | DPYSL2 | SIGNOR-249042 |
| ROCK1 | phosphorylation → unknown | DES | SIGNOR-249032 |
| ROCK1 | phosphorylation down-regulates | ARHGAP35 | SIGNOR-182849 |
| ROCK1 | phosphorylation → up-regulates activity | ARHGAP24 | SIGNOR-249309 |