Entity Details

Name EGFR_Tyr373
ID Q13480
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCGAB1Tyr373ASDTDSSyCIPTAGMphosphorylation
up-regulates activity		19881549SIGNOR-236318
EGFRGAB1Tyr373ASDTDSSyCIPTAGMphosphorylation
up-regulates activity		9890893SIGNOR-236408
INSRGAB1Tyr373ASDTDSSyCIPTAGMphosphorylation
up-regulates activity		10978177SIGNOR-251312
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
GAB1
PTyr373		phosphorylation
up-regulates
→		GAB119881549SIGNOR-236318
EGFRphosphorylation
up-regulates
→
GAB1
PTyr373		phosphorylation
up-regulates
→		GAB19890893SIGNOR-236408
INSRphosphorylation
up-regulates
→
GAB1
PTyr373		phosphorylation
up-regulates
→		GAB110978177SIGNOR-251312
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		GAB1SIGNOR-236318
EGFRphosphorylation
→
up-regulates activity 		GAB1SIGNOR-236408
INSRphosphorylation
→
up-regulates activity 		GAB1SIGNOR-251312