Entity Details

Name ERK1/2_Ser454
ID Q13480
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK3GAB1Ser454YVPMNPNsPPRQHSSphosphorylation
up-regulates activity		15379552SIGNOR-249460
MAPK1GAB1Ser454YVPMNPNsPPRQHSSphosphorylation
up-regulates activity		15379552SIGNOR-249396
ERK1/2GAB1Ser454YVPMNPNsPPRQHSSphosphorylation
up-regulates activity		15379552SIGNOR-129188
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK3phosphorylation
up-regulates
→
GAB1
PSer454		phosphorylation
up-regulates
→		GAB115379552SIGNOR-249460
MAPK1phosphorylation
up-regulates
→
GAB1
PSer454		phosphorylation
up-regulates
→		GAB115379552SIGNOR-249396
ERK1/2phosphorylation
up-regulates
→
GAB1
PSer454		phosphorylation
up-regulates
→		GAB115379552SIGNOR-129188
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK3phosphorylation
→
up-regulates activity 		GAB1SIGNOR-249460
MAPK1phosphorylation
→
up-regulates activity 		GAB1SIGNOR-249396
ERK1/2phosphorylation
→
up-regulates activity 		GAB1SIGNOR-129188