Entity Details

Name ERK1/2_Thr476
ID Q13480
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1GAB1Thr476EANYVPMtPGTFDFSphosphorylation
up-regulates activity		15379552SIGNOR-249400
MAPK3GAB1Thr476EANYVPMtPGTFDFSphosphorylation
up-regulates activity		15379552SIGNOR-249464
ERK1/2GAB1Thr476EANYVPMtPGTFDFSphosphorylation
up-regulates activity		15379552SIGNOR-129200
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
GAB1
PThr476		phosphorylation
up-regulates
→		GAB115379552SIGNOR-249400
MAPK3phosphorylation
up-regulates
→
GAB1
PThr476		phosphorylation
up-regulates
→		GAB115379552SIGNOR-249464
ERK1/2phosphorylation
up-regulates
→
GAB1
PThr476		phosphorylation
up-regulates
→		GAB115379552SIGNOR-129200
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
up-regulates activity 		GAB1SIGNOR-249400
MAPK3phosphorylation
→
up-regulates activity 		GAB1SIGNOR-249464
ERK1/2phosphorylation
→
up-regulates activity 		GAB1SIGNOR-129200