Entity Details

Name INSR_Tyr472
ID Q13480
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
INSRGAB1Tyr472EPIQEANyVPMTPGTphosphorylation
up-regulates activity		10978177SIGNOR-251314
EGFRGAB1Tyr472EPIQEANyVPMTPGTphosphorylation
up-regulates activity		9890893SIGNOR-236412
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
INSRphosphorylation
up-regulates
→
GAB1
PTyr472		phosphorylation
up-regulates
→		GAB110978177SIGNOR-251314
EGFRphosphorylation
up-regulates
→
GAB1
PTyr472		phosphorylation
up-regulates
→		GAB19890893SIGNOR-236412
Regulator Mechanism/Effect Target SIGNOR-ID
INSRphosphorylation
→
up-regulates activity 		GAB1SIGNOR-251314
EGFRphosphorylation
→
up-regulates activity 		GAB1SIGNOR-236412