Entity Details

Name ERK1/2_Thr277
ID Q13485
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK3SMAD4Thr277GSRTAPYtPNLPHHQphosphorylation
up-regulates		12801888SIGNOR-101664
MAPK1SMAD4Thr277GSRTAPYtPNLPHHQphosphorylation
up-regulates		12801888SIGNOR-101660
ERK1/2SMAD4Thr277GSRTAPYtPNLPHHQphosphorylation
up-regulates		12801888SIGNOR-244739
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK3phosphorylation
up-regulates
→
SMAD4
PThr277		phosphorylation
up-regulates
→		SMAD412801888SIGNOR-101664
MAPK1phosphorylation
up-regulates
→
SMAD4
PThr277		phosphorylation
up-regulates
→		SMAD412801888SIGNOR-101660
ERK1/2phosphorylation
up-regulates
→
SMAD4
PThr277		phosphorylation
up-regulates
→		SMAD412801888SIGNOR-244739
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK3phosphorylation
→
up-regulates 		SMAD4SIGNOR-101664
MAPK1phosphorylation
→
up-regulates 		SMAD4SIGNOR-101660
ERK1/2phosphorylation
→
up-regulates 		SMAD4SIGNOR-244739