Entity Details

Name GSK3B_Thr273
ID Q13485
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BSMAD4Thr273TTWTGSRtAPYTPNLphosphorylation
down-regulates quantity by destabilization		25373906SIGNOR-276440
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
SMAD4
PThr273		phosphorylation
down-regulates
⊣		SMAD425373906SIGNOR-276440
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		SMAD4SIGNOR-276440