Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CDK1	SQSTM1	Ser272 View in OncoXplorer	RSRLTPVsPESSSTE	phosphorylation up-regulates	20974803	SIGNOR-169012
CSNK1A1	SQSTM1	Ser349	SSKEVDPsTGELQSL	phosphorylation up-regulates activity	37723657	SIGNOR-273769
CyclinB/CDK1	SQSTM1	Thr269 View in OncoXplorer	GGKRSRLtPVSPESS	phosphorylation up-regulates	20974803	SIGNOR-216936
EGFR	SQSTM1	Tyr433	AALDTIQySKHPPPL	phosphorylation down-regulates activity	31931029	SIGNOR-277500
ULK1	SQSTM1	Ser403	ESLSQMLsMGFSDEG	phosphorylation down-regulates quantity by destabilization	25040165	SIGNOR-278349
MELK	SQSTM1	–		phosphorylation up-regulates activity	29212029	SIGNOR-279544
PRKCD	SQSTM1	Ser349	SSKEVDPsTGELQSL	phosphorylation up-regulates activity	28846113	SIGNOR-280086
MAP3K3	SQSTM1	Thr269 View in OncoXplorer	GGKRSRLtPVSPESS	phosphorylation up-regulates activity	26279575	SIGNOR-279532
MAP3K3	SQSTM1	Ser272 View in OncoXplorer	RSRLTPVsPESSSTE	phosphorylation up-regulates activity	26279575	SIGNOR-279533
CDK1	SQSTM1	Thr269 View in OncoXplorer	GGKRSRLtPVSPESS	phosphorylation up-regulates	20974803	SIGNOR-169016
TBK1	SQSTM1	Ser403	ESLSQMLsMGFSDEG	phosphorylation up-regulates	22921120	SIGNOR-191944
CyclinB/CDK1	SQSTM1	Ser272 View in OncoXplorer	RSRLTPVsPESSSTE	phosphorylation up-regulates	20974803	SIGNOR-216932

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CDK1	phosphorylation up-regulates →	SQSTM1 PSer272	phosphorylation up-regulates →	SQSTM1	20974803	SIGNOR-169012
CSNK1A1	phosphorylation up-regulates →	SQSTM1 PSer349	phosphorylation up-regulates →	SQSTM1	37723657	SIGNOR-273769
CyclinB/CDK1	phosphorylation up-regulates →	SQSTM1 PThr269	phosphorylation up-regulates →	SQSTM1	20974803	SIGNOR-216936
EGFR	phosphorylation up-regulates →	SQSTM1 PTyr433	phosphorylation down-regulates ⊣	SQSTM1	31931029	SIGNOR-277500
ULK1	phosphorylation up-regulates →	SQSTM1 PSer403	phosphorylation down-regulates ⊣	SQSTM1	25040165	SIGNOR-278349
PRKCD	phosphorylation up-regulates →	SQSTM1 PSer349	phosphorylation up-regulates →	SQSTM1	28846113	SIGNOR-280086
MAP3K3	phosphorylation up-regulates →	SQSTM1 PThr269	phosphorylation up-regulates →	SQSTM1	26279575	SIGNOR-279532
MAP3K3	phosphorylation up-regulates →	SQSTM1 PSer272	phosphorylation up-regulates →	SQSTM1	26279575	SIGNOR-279533
CDK1	phosphorylation up-regulates →	SQSTM1 PThr269	phosphorylation up-regulates →	SQSTM1	20974803	SIGNOR-169016
TBK1	phosphorylation up-regulates →	SQSTM1 PSer403	phosphorylation up-regulates →	SQSTM1	22921120	SIGNOR-191944
CyclinB/CDK1	phosphorylation up-regulates →	SQSTM1 PSer272	phosphorylation up-regulates →	SQSTM1	20974803	SIGNOR-216932

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CDK1	phosphorylation → up-regulates	SQSTM1	SIGNOR-169012
CSNK1A1	phosphorylation → up-regulates activity	SQSTM1	SIGNOR-273769
CyclinB/CDK1	phosphorylation → up-regulates	SQSTM1	SIGNOR-216936
EGFR	phosphorylation → down-regulates activity	SQSTM1	SIGNOR-277500
ULK1	phosphorylation down-regulates quantity by destabilization	SQSTM1	SIGNOR-278349
MELK	phosphorylation → up-regulates activity	SQSTM1	SIGNOR-279544
PRKCD	phosphorylation → up-regulates activity	SQSTM1	SIGNOR-280086
MAP3K3	phosphorylation → up-regulates activity	SQSTM1	SIGNOR-279532
MAP3K3	phosphorylation → up-regulates activity	SQSTM1	SIGNOR-279533
CDK1	phosphorylation → up-regulates	SQSTM1	SIGNOR-169016
TBK1	phosphorylation → up-regulates	SQSTM1	SIGNOR-191944
CyclinB/CDK1	phosphorylation → up-regulates	SQSTM1	SIGNOR-216932