| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | SQSTM1 | Tyr433 | AALDTIQySKHPPPL | phosphorylation down-regulates activity | 31931029 | SIGNOR-277500 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | phosphorylation up-regulates → | SQSTM1 PTyr433 | phosphorylation down-regulates ⊣ | SQSTM1 | 31931029 | SIGNOR-277500 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EGFR | phosphorylation → down-regulates activity | SQSTM1 | SIGNOR-277500 |
