| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | EIF4EBP1 | Ser65 | FLMECRNsPVTKTPP | phosphorylation down-regulates activity | 10942774 | SIGNOR-226714 |
| MTOR | EIF4EBP1 | Thr36 | LPPGDYStTPGGTLF | phosphorylation down-regulates activity | 9465032 | SIGNOR-55697 |
| mTORC1 | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation down-regulates activity | 23486913 | SIGNOR-217114 |
| GSK3B | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation down-regulates activity | 18701453 | SIGNOR-236660 |
| MTOR | EIF4EBP1 | Ser83 | PTIPGVTsPSSDEPP | phosphorylation down-regulates activity | 9204908 | SIGNOR-250292 |
| RPS6KA5 | EIF4EBP1 | Thr37 | PPGDYSTtPGGTLFS | phosphorylation down-regulates activity | 12213813 | SIGNOR-262991 |
| MTOR | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation down-regulates activity | 23486913 | SIGNOR-219266 |
| CDK13 | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation up-regulates activity | 36882522 | SIGNOR-273113 |
| mTORC1 | EIF4EBP1 | – | phosphorylation down-regulates activity | 12747827 | SIGNOR-236678 | |
| CSNK2A1 | EIF4EBP1 | Ser112 | KRAGGEEsQFEMDI | phosphorylation down-regulates | 12588975 | SIGNOR-98280 |
| RPS6KA5 | EIF4EBP1 | Thr45 | PGGTLFStTPGGTRI | phosphorylation down-regulates activity | 11777913 | SIGNOR-249131 |
| MTOR | EIF4EBP1 | Ser65 | FLMECRNsPVTKTPP | phosphorylation down-regulates activity | 12747827 | SIGNOR-101115 |
| MAPK1 | EIF4EBP1 | Ser65 | FLMECRNsPVTKTPP | phosphorylation down-regulates activity | 11691836 | SIGNOR-249390 |
| MAPK14 | EIF4EBP1 | Ser65 | FLMECRNsPVTKTPP | phosphorylation down-regulates activity | 11777913 | SIGNOR-250097 |
| MAPK1 | EIF4EBP1 | Ser83 | PTIPGVTsPSSDEPP | phosphorylation down-regulates activity | 11691836 | SIGNOR-249391 |
| MTOR | EIF4EBP1 | Thr37 | PPGDYSTtPGGTLFS | phosphorylation down-regulates activity | 23486913 | SIGNOR-219262 |
| RPS6KA5 | EIF4EBP1 | Ser65 | FLMECRNsPVTKTPP | phosphorylation down-regulates activity | 12213813 | SIGNOR-262993 |
| mTORC1 | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation down-regulates activity | 12747827 | SIGNOR-236698 |
| MTOR | EIF4EBP1 | Thr45 | PGGTLFStTPGGTRI | phosphorylation down-regulates activity | 17510057 | SIGNOR-154814 |
| mTORC1 | EIF4EBP1 | – | phosphorylation down-regulates activity | 17510057 | SIGNOR-235748 | |
| MTOR | EIF4EBP1 | Thr70 | RNSPVTKtPPRDLPT | phosphorylation down-regulates activity | 10942774 | SIGNOR-80797 |
| mTORC1 | EIF4EBP1 | Thr70 | RNSPVTKtPPRDLPT | phosphorylation down-regulates activity | 12747827 | SIGNOR-235964 |
| CSNK2A2 | EIF4EBP1 | Ser112 | KRAGGEEsQFEMDI | phosphorylation down-regulates activity | 9806882 | SIGNOR-249334 |
| MTOR | EIF4EBP1 | Thr45 | PGGTLFStTPGGTRI | phosphorylation down-regulates activity | 20670887 | SIGNOR-167184 |
| GSK3B | EIF4EBP1 | Thr37 | PPGDYSTtPGGTLFS | phosphorylation down-regulates activity | 18701453 | SIGNOR-236026 |
| ATM | EIF4EBP1 | Ser112 | KRAGGEEsQFEMDI | phosphorylation down-regulates | 11146653 | SIGNOR-85619 |
| PIM2 | EIF4EBP1 | – | phosphorylation up-regulates activity | 19290049 | SIGNOR-279091 | |
| MAPK14 | EIF4EBP1 | Thr37 | PPGDYSTtPGGTLFS | phosphorylation down-regulates activity | 11777913 | SIGNOR-250098 |
| mTORC1 | EIF4EBP1 | – | phosphorylation down-regulates activity | 20670887 | SIGNOR-235745 | |
| MTOR | EIF4EBP1 | Thr36 | LPPGDYStTPGGTLF | phosphorylation down-regulates activity | 17510057 | SIGNOR-154810 |
| MTOR | EIF4EBP1 | Thr70 | RNSPVTKtPPRDLPT | phosphorylation down-regulates activity | 10942774 | SIGNOR-226710 |
| MTOR | EIF4EBP1 | Thr36 | LPPGDYStTPGGTLF | phosphorylation down-regulates activity | 20670887 | SIGNOR-167180 |
| mTORC1 | EIF4EBP1 | Ser65 | FLMECRNsPVTKTPP | phosphorylation down-regulates activity | 12747827 | SIGNOR-236690 |
| MAPK1 | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation down-regulates activity | 11691836 | SIGNOR-249393 |
| mTORC1 | EIF4EBP1 | Thr45 | PGGTLFStTPGGTRI | phosphorylation down-regulates activity | 9465032 | SIGNOR-217090 |
| mTORC1 | EIF4EBP1 | Thr70 | RNSPVTKtPPRDLPT | phosphorylation down-regulates activity | 23486913 | SIGNOR-217141 |
| mTORC1 | EIF4EBP1 | Thr37 | PPGDYSTtPGGTLFS | phosphorylation down-regulates activity | 23486913 | SIGNOR-217110 |
| MTOR | EIF4EBP1 | Ser65 | FLMECRNsPVTKTPP | phosphorylation down-regulates activity | 23486913 | SIGNOR-219257 |
| MAPK1 | EIF4EBP1 | Thr70 | RNSPVTKtPPRDLPT | phosphorylation down-regulates activity | 11691836 | SIGNOR-249394 |
| mTORC1 | EIF4EBP1 | Thr70 | RNSPVTKtPPRDLPT | phosphorylation down-regulates activity | 10942774 | SIGNOR-236702 |
| mTORC1 | EIF4EBP1 | Ser65 | FLMECRNsPVTKTPP | phosphorylation down-regulates activity | 23486913 | SIGNOR-217137 |
| PRKCD | EIF4EBP1 | – | phosphorylation down-regulates activity | 10698949 | SIGNOR-279100 | |
| RPS6KA5 | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation down-regulates activity | 12213813 | SIGNOR-262992 |
| CSNK1E | EIF4EBP1 | Thr50 | FSTTPGGtRIIYDRK | phosphorylation down-regulates | 24247720 | SIGNOR-203276 |
| MTOR | EIF4EBP1 | Thr70 | RNSPVTKtPPRDLPT | phosphorylation down-regulates activity | 23486913 | SIGNOR-219273 |
| CSNK1E | EIF4EBP1 | Thr41 | YSTTPGGtLFSTTPG | phosphorylation down-regulates | 24247720 | SIGNOR-203240 |
| MAPK1 | EIF4EBP1 | Thr37 | PPGDYSTtPGGTLFS | phosphorylation down-regulates activity | 11691836 | SIGNOR-249392 |
| RPS6KA5 | EIF4EBP1 | Thr70 | RNSPVTKtPPRDLPT | phosphorylation down-regulates activity | 12213813 | SIGNOR-262994 |
| MTOR | EIF4EBP1 | Thr70 | RNSPVTKtPPRDLPT | phosphorylation down-regulates activity | 12747827 | SIGNOR-101127 |
| MTOR | EIF4EBP1 | Thr37 | PPGDYSTtPGGTLFS | phosphorylation down-regulates activity | 12747827 | SIGNOR-101119 |
| CyclinK/CDK13 | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation up-regulates activity | 36882522 | SIGNOR-273114 |
| MAPK1 | EIF4EBP1 | Thr45 | PGGTLFStTPGGTRI | phosphorylation down-regulates | 11777913 | SIGNOR-113563 |
| mTORC1 | EIF4EBP1 | Thr37 | PPGDYSTtPGGTLFS | phosphorylation down-regulates activity | 12747827 | SIGNOR-236694 |
| MTOR | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation down-regulates activity | 12747827 | SIGNOR-101123 |
| mTORC1 | EIF4EBP1 | Thr36 | LPPGDYStTPGGTLF | phosphorylation down-regulates activity | 9465032 | SIGNOR-217086 |
| CDK1 | EIF4EBP1 | Thr70 | RNSPVTKtPPRDLPT | phosphorylation down-regulates activity | 11553333 | SIGNOR-110416 |
| MAPK14 | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation down-regulates activity | 11777913 | SIGNOR-250099 |
| MTOR | EIF4EBP1 | Thr45 | PGGTLFStTPGGTRI | phosphorylation down-regulates activity | 9465032 | SIGNOR-55701 |
| GSK3B | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation down-regulates activity | 23584478 | SIGNOR-201699 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PSer65 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 10942774 | SIGNOR-226714 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr36 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 9465032 | SIGNOR-55697 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 23486913 | SIGNOR-217114 |
| GSK3B | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 18701453 | SIGNOR-236660 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PSer83 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 9204908 | SIGNOR-250292 |
| RPS6KA5 | phosphorylation up-regulates → | EIF4EBP1 PThr37 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12213813 | SIGNOR-262991 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 23486913 | SIGNOR-219266 |
| CDK13 | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation up-regulates → | EIF4EBP1 | 36882522 | SIGNOR-273113 |
| CSNK2A1 | phosphorylation up-regulates → | EIF4EBP1 PSer112 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12588975 | SIGNOR-98280 |
| RPS6KA5 | phosphorylation up-regulates → | EIF4EBP1 PThr45 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11777913 | SIGNOR-249131 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PSer65 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12747827 | SIGNOR-101115 |
| MAPK1 | phosphorylation up-regulates → | EIF4EBP1 PSer65 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11691836 | SIGNOR-249390 |
| MAPK14 | phosphorylation up-regulates → | EIF4EBP1 PSer65 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11777913 | SIGNOR-250097 |
| MAPK1 | phosphorylation up-regulates → | EIF4EBP1 PSer83 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11691836 | SIGNOR-249391 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr37 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 23486913 | SIGNOR-219262 |
| RPS6KA5 | phosphorylation up-regulates → | EIF4EBP1 PSer65 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12213813 | SIGNOR-262993 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12747827 | SIGNOR-236698 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr45 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 17510057 | SIGNOR-154814 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr70 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 10942774 | SIGNOR-80797 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PThr70 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12747827 | SIGNOR-235964 |
| CSNK2A2 | phosphorylation up-regulates → | EIF4EBP1 PSer112 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 9806882 | SIGNOR-249334 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr45 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 20670887 | SIGNOR-167184 |
| GSK3B | phosphorylation up-regulates → | EIF4EBP1 PThr37 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 18701453 | SIGNOR-236026 |
| ATM | phosphorylation up-regulates → | EIF4EBP1 PSer112 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11146653 | SIGNOR-85619 |
| MAPK14 | phosphorylation up-regulates → | EIF4EBP1 PThr37 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11777913 | SIGNOR-250098 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr36 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 17510057 | SIGNOR-154810 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr70 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 10942774 | SIGNOR-226710 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr36 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 20670887 | SIGNOR-167180 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PSer65 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12747827 | SIGNOR-236690 |
| MAPK1 | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11691836 | SIGNOR-249393 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PThr45 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 9465032 | SIGNOR-217090 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PThr70 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 23486913 | SIGNOR-217141 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PThr37 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 23486913 | SIGNOR-217110 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PSer65 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 23486913 | SIGNOR-219257 |
| MAPK1 | phosphorylation up-regulates → | EIF4EBP1 PThr70 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11691836 | SIGNOR-249394 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PThr70 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 10942774 | SIGNOR-236702 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PSer65 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 23486913 | SIGNOR-217137 |
| RPS6KA5 | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12213813 | SIGNOR-262992 |
| CSNK1E | phosphorylation up-regulates → | EIF4EBP1 PThr50 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 24247720 | SIGNOR-203276 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr70 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 23486913 | SIGNOR-219273 |
| CSNK1E | phosphorylation up-regulates → | EIF4EBP1 PThr41 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 24247720 | SIGNOR-203240 |
| MAPK1 | phosphorylation up-regulates → | EIF4EBP1 PThr37 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11691836 | SIGNOR-249392 |
| RPS6KA5 | phosphorylation up-regulates → | EIF4EBP1 PThr70 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12213813 | SIGNOR-262994 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr70 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12747827 | SIGNOR-101127 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr37 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12747827 | SIGNOR-101119 |
| CyclinK/CDK13 | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation up-regulates → | EIF4EBP1 | 36882522 | SIGNOR-273114 |
| MAPK1 | phosphorylation up-regulates → | EIF4EBP1 PThr45 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11777913 | SIGNOR-113563 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PThr37 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12747827 | SIGNOR-236694 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12747827 | SIGNOR-101123 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PThr36 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 9465032 | SIGNOR-217086 |
| CDK1 | phosphorylation up-regulates → | EIF4EBP1 PThr70 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11553333 | SIGNOR-110416 |
| MAPK14 | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11777913 | SIGNOR-250099 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr45 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 9465032 | SIGNOR-55701 |
| GSK3B | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 23584478 | SIGNOR-201699 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-226714 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-55697 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-217114 |
| GSK3B | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-236660 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-250292 |
| RPS6KA5 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-262991 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-219266 |
| CDK13 | phosphorylation → up-regulates activity | EIF4EBP1 | SIGNOR-273113 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-236678 |
| CSNK2A1 | phosphorylation![]() down-regulates | EIF4EBP1 | SIGNOR-98280 |
| RPS6KA5 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-249131 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-101115 |
| MAPK1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-249390 |
| MAPK14 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-250097 |
| MAPK1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-249391 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-219262 |
| RPS6KA5 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-262993 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-236698 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-154814 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-235748 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-80797 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-235964 |
| CSNK2A2 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-249334 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-167184 |
| GSK3B | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-236026 |
| ATM | phosphorylation![]() down-regulates | EIF4EBP1 | SIGNOR-85619 |
| PIM2 | phosphorylation → up-regulates activity | EIF4EBP1 | SIGNOR-279091 |
| MAPK14 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-250098 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-235745 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-154810 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-226710 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-167180 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-236690 |
| MAPK1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-249393 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-217090 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-217141 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-217110 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-219257 |
| MAPK1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-249394 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-236702 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-217137 |
| PRKCD | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-279100 |
| RPS6KA5 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-262992 |
| CSNK1E | phosphorylation![]() down-regulates | EIF4EBP1 | SIGNOR-203276 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-219273 |
| CSNK1E | phosphorylation![]() down-regulates | EIF4EBP1 | SIGNOR-203240 |
| MAPK1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-249392 |
| RPS6KA5 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-262994 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-101127 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-101119 |
| CyclinK/CDK13 | phosphorylation → up-regulates activity | EIF4EBP1 | SIGNOR-273114 |
| MAPK1 | phosphorylation![]() down-regulates | EIF4EBP1 | SIGNOR-113563 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-236694 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-101123 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-217086 |
| CDK1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-110416 |
| MAPK14 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-250099 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-55701 |
| GSK3B | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-201699 |