| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A2 | EIF4EBP1 | Ser112 | KRAGGEEsQFEMDI | phosphorylation down-regulates activity | 9806882 | SIGNOR-249334 |
| ATM | EIF4EBP1 | Ser112 | KRAGGEEsQFEMDI | phosphorylation down-regulates | 11146653 | SIGNOR-85619 |
| CSNK2A1 | EIF4EBP1 | Ser112 | KRAGGEEsQFEMDI | phosphorylation down-regulates | 12588975 | SIGNOR-98280 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A2 | phosphorylation up-regulates → | EIF4EBP1 PSer112 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 9806882 | SIGNOR-249334 |
| ATM | phosphorylation up-regulates → | EIF4EBP1 PSer112 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11146653 | SIGNOR-85619 |
| CSNK2A1 | phosphorylation up-regulates → | EIF4EBP1 PSer112 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 12588975 | SIGNOR-98280 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A2 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-249334 |
| ATM | phosphorylation down-regulates | EIF4EBP1 | SIGNOR-85619 |
| CSNK2A1 | phosphorylation down-regulates | EIF4EBP1 | SIGNOR-98280 |
