| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | EIF4EBP1 | Thr36 | LPPGDYStTPGGTLF | phosphorylation down-regulates activity | 17510057 | SIGNOR-154810 |
| MTOR | EIF4EBP1 | Thr36 | LPPGDYStTPGGTLF | phosphorylation down-regulates activity | 20670887 | SIGNOR-167180 |
| mTORC1 | EIF4EBP1 | Thr36 | LPPGDYStTPGGTLF | phosphorylation down-regulates activity | 9465032 | SIGNOR-217086 |
| MTOR | EIF4EBP1 | Thr36 | LPPGDYStTPGGTLF | phosphorylation down-regulates activity | 9465032 | SIGNOR-55697 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr36 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 17510057 | SIGNOR-154810 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr36 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 20670887 | SIGNOR-167180 |
| mTORC1 | phosphorylation up-regulates → | EIF4EBP1 PThr36 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 9465032 | SIGNOR-217086 |
| MTOR | phosphorylation up-regulates → | EIF4EBP1 PThr36 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 9465032 | SIGNOR-55697 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-154810 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-167180 |
| mTORC1 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-217086 |
| MTOR | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-55697 |