| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TBK1 | RIPK1 | Thr189 | TAKKNGGtLYYMAPE | phosphorylation down-regulates activity | 30146158 | SIGNOR-279388 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TBK1 | phosphorylation up-regulates → | RIPK1 PThr189 | phosphorylation down-regulates ⊣ | RIPK1 | 30146158 | SIGNOR-279388 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| TBK1 | phosphorylation → down-regulates activity | RIPK1 | SIGNOR-279388 |