Entity Details

Name	HDAC1
ID	Q13547
Role	substrate
Enzymatic Domains
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Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CSNK2A1	HDAC1	Ser423 View in OncoXplorer	CEEEFSDsEEEGEGG	phosphorylation up-regulates	11602581	SIGNOR-111015
PBK	HDAC1	–		phosphorylation up-regulates activity	29896413	SIGNOR-279086
ABL1	HDAC1	–		phosphorylation up-regulates activity	25561363	SIGNOR-280169
CSNK2A1	HDAC1	Ser421 View in OncoXplorer	IACEEEFsDSEEEGE	phosphorylation up-regulates	11602581	SIGNOR-111011
CSNK2A2	HDAC1	Ser423 View in OncoXplorer	CEEEFSDsEEEGEGG	phosphorylation up-regulates activity	11602581	SIGNOR-251000
CSNK2A2	HDAC1	Ser421 View in OncoXplorer	IACEEEFsDSEEEGE	phosphorylation up-regulates activity	11602581	SIGNOR-250999

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CSNK2A1	phosphorylation up-regulates →	HDAC1 PSer423	phosphorylation up-regulates →	HDAC1	11602581	SIGNOR-111015
CSNK2A1	phosphorylation up-regulates →	HDAC1 PSer421	phosphorylation up-regulates →	HDAC1	11602581	SIGNOR-111011
CSNK2A2	phosphorylation up-regulates →	HDAC1 PSer423	phosphorylation up-regulates →	HDAC1	11602581	SIGNOR-251000
CSNK2A2	phosphorylation up-regulates →	HDAC1 PSer421	phosphorylation up-regulates →	HDAC1	11602581	SIGNOR-250999

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CSNK2A1	phosphorylation → up-regulates	HDAC1	SIGNOR-111015
PBK	phosphorylation → up-regulates activity	HDAC1	SIGNOR-279086
ABL1	phosphorylation → up-regulates activity	HDAC1	SIGNOR-280169
CSNK2A1	phosphorylation → up-regulates	HDAC1	SIGNOR-111011
CSNK2A2	phosphorylation → up-regulates activity	HDAC1	SIGNOR-251000
CSNK2A2	phosphorylation → up-regulates activity	HDAC1	SIGNOR-250999