Entity Details

Name CAMK2D
ID Q13557
Role kinase
Enzymatic Domains
Protein kinase 14-272
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CAMK2DANKRD28Ser1011TNTSKTVsFEALPIMphosphorylation
down-regulates activity
17023142SIGNOR-264793
CAMK2DVIMSer83GVRLLQDsVDFSLADphosphorylation
unknown
16140754SIGNOR-250690
CAMK2DCEACAM1Thr457CFLHFGKtGRASDQRphosphorylation
up-regulates
24302721SIGNOR-203402
CAMK2DKCNQ1Ser484PHFMRTNsFAEDLDLphosphorylation
down-regulates activity
29410121SIGNOR-275479
CAMK2DTPD52Ser176KNSPTFKsFEEKVENphosphorylation
unknown
20032513SIGNOR-162630
CAMK2DTPD52Ser176KNSPTFKsFEEKVENphosphorylation
unknown
20946871SIGNOR-168550
CAMK2DHDAC4Ser210YGKTQHSsLDQSSPPphosphorylation
up-regulates
17179159SIGNOR-151418
CAMK2DCACNB2Thr554RGLSRQEtFDSETQEphosphorylation
up-regulates
20194790SIGNOR-164067
CAMK2DCAMK2Dphosphorylation
up-regulates
19725819SIGNOR-255954
CAMK2DSCN5ASer516LSLTRGLsRTSMKPRphosphorylation
down-regulates
22514276SIGNOR-197058
CAMK2DSCN5AThr594LHGKKNStVDCNGVVphosphorylation
down-regulates
22514276SIGNOR-197067
CAMK2DSCN5ASer1934LFRQQAGsGLSEEDAphosphorylation
up-regulates activity
28882890SIGNOR-275782
CAMK2DSCN5ASer1985DSVTRATsDNLQVRGphosphorylation
up-regulates activity
28882890SIGNOR-275783
CAMK2DSCN5ASer516LSLTRGLsRTSMKPRphosphorylation
up-regulates activity
33410863SIGNOR-275776
CAMK2DSCN5ASer571PWPLRRTsAQGQPSPphosphorylation
up-regulates activity
33410863SIGNOR-275777
CAMK2DSCN5AThr594LHGKKNStVDCNGVVphosphorylation
up-regulates activity
33410863SIGNOR-275778
CAMK2DITPR2Ser150EKNAMRVsLDAAGNEphosphorylation
down-regulates activity
23019322SIGNOR-262692
CAMK2DKCNJ11Thr224MQVVRKTtSPEGEVVphosphorylation
down-regulates
23223335SIGNOR-200027
CAMK2DSCN8ASer561PFLSRHNsKSSIFSFphosphorylation
up-regulates activity
32611770SIGNOR-275790
CAMK2DSCN8ASer641RRSVKRNsTVDCNGVphosphorylation
up-regulates activity
32611770SIGNOR-275791
CAMK2DSCN8AThr642RSVKRNStVDCNGVVphosphorylation
up-regulates activity
32611770SIGNOR-275792
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CAMK2Dphosphorylation
up-regulates
ANKRD28
PSer1011
phosphorylation
down-regulates
ANKRD2817023142SIGNOR-264793
CAMK2Dphosphorylation
up-regulates
VIM
PSer83
phosphorylation
down-regulates
VIM16140754SIGNOR-250690
CAMK2Dphosphorylation
up-regulates
CEACAM1
PThr457
phosphorylation
up-regulates
CEACAM124302721SIGNOR-203402
CAMK2Dphosphorylation
up-regulates
KCNQ1
PSer484
phosphorylation
down-regulates
KCNQ129410121SIGNOR-275479
CAMK2Dphosphorylation
up-regulates
TPD52
PSer176
phosphorylation
down-regulates
TPD5220032513SIGNOR-162630
CAMK2Dphosphorylation
up-regulates
TPD52
PSer176
phosphorylation
down-regulates
TPD5220946871SIGNOR-168550
CAMK2Dphosphorylation
up-regulates
HDAC4
PSer210
phosphorylation
up-regulates
HDAC417179159SIGNOR-151418
CAMK2Dphosphorylation
up-regulates
CACNB2
PThr554
phosphorylation
up-regulates
CACNB220194790SIGNOR-164067
CAMK2Dphosphorylation
up-regulates
SCN5A
PSer516
phosphorylation
down-regulates
SCN5A22514276SIGNOR-197058
CAMK2Dphosphorylation
up-regulates
SCN5A
PThr594
phosphorylation
down-regulates
SCN5A22514276SIGNOR-197067
CAMK2Dphosphorylation
up-regulates
SCN5A
PSer1934
phosphorylation
up-regulates
SCN5A28882890SIGNOR-275782
CAMK2Dphosphorylation
up-regulates
SCN5A
PSer1985
phosphorylation
up-regulates
SCN5A28882890SIGNOR-275783
CAMK2Dphosphorylation
up-regulates
SCN5A
PSer516
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275776
CAMK2Dphosphorylation
up-regulates
SCN5A
PSer571
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275777
CAMK2Dphosphorylation
up-regulates
SCN5A
PThr594
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275778
CAMK2Dphosphorylation
up-regulates
ITPR2
PSer150
phosphorylation
down-regulates
ITPR223019322SIGNOR-262692
CAMK2Dphosphorylation
up-regulates
KCNJ11
PThr224
phosphorylation
down-regulates
KCNJ1123223335SIGNOR-200027
CAMK2Dphosphorylation
up-regulates
SCN8A
PSer561
phosphorylation
up-regulates
SCN8A32611770SIGNOR-275790
CAMK2Dphosphorylation
up-regulates
SCN8A
PSer641
phosphorylation
up-regulates
SCN8A32611770SIGNOR-275791
CAMK2Dphosphorylation
up-regulates
SCN8A
PThr642
phosphorylation
up-regulates
SCN8A32611770SIGNOR-275792
Regulator Mechanism/Effect Target SIGNOR-ID
CAMK2Dphosphorylation

down-regulates activity
ANKRD28SIGNOR-264793
CAMK2Dphosphorylation

unknown
VIMSIGNOR-250690
CAMK2Dphosphorylation

up-regulates
CEACAM1SIGNOR-203402
CAMK2Dphosphorylation

down-regulates activity
KCNQ1SIGNOR-275479
CAMK2Dphosphorylation

unknown
TPD52SIGNOR-162630
CAMK2Dphosphorylation

unknown
TPD52SIGNOR-168550
CAMK2Dphosphorylation

up-regulates
HDAC4SIGNOR-151418
CAMK2Dphosphorylation

up-regulates
CACNB2SIGNOR-164067
CAMK2Dphosphorylation

up-regulates
CAMK2DSIGNOR-255954
CAMK2Dphosphorylation
img/direct_inhibition.png
down-regulates
SCN5ASIGNOR-197058
CAMK2Dphosphorylation
img/direct_inhibition.png
down-regulates
SCN5ASIGNOR-197067
CAMK2Dphosphorylation

up-regulates activity
SCN5ASIGNOR-275782
CAMK2Dphosphorylation

up-regulates activity
SCN5ASIGNOR-275783
CAMK2Dphosphorylation

up-regulates activity
SCN5ASIGNOR-275776
CAMK2Dphosphorylation

up-regulates activity
SCN5ASIGNOR-275777
CAMK2Dphosphorylation

up-regulates activity
SCN5ASIGNOR-275778
CAMK2Dphosphorylation

down-regulates activity
ITPR2SIGNOR-262692
CAMK2Dphosphorylation
img/direct_inhibition.png
down-regulates
KCNJ11SIGNOR-200027
CAMK2Dphosphorylation

up-regulates activity
SCN8ASIGNOR-275790
CAMK2Dphosphorylation

up-regulates activity
SCN8ASIGNOR-275791
CAMK2Dphosphorylation

up-regulates activity
SCN8ASIGNOR-275792