| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| OXSR1 | SLC12A1 | Thr100 | TNTYYLQtFGHNTMD | phosphorylation up-regulates activity | 21321328 | SIGNOR-276311 |
| AMPK | SLC12A1 | Ser122 | YRNTGSIsGPKVNRP | phosphorylation up-regulates activity | 17341212 | SIGNOR-263103 |
| OXSR1 | SLC12A1 | Ser91 | ASFHAYDsHTNTYYL | phosphorylation up-regulates activity | 21321328 | SIGNOR-276312 |
| STK39 | SLC12A1 | Thr100 | TNTYYLQtFGHNTMD | phosphorylation up-regulates activity | 21321328 | SIGNOR-276307 |
| STK39 | SLC12A1 | Ser91 | ASFHAYDsHTNTYYL | phosphorylation up-regulates activity | 21321328 | SIGNOR-276308 |
| STK39 | SLC12A1 | Thr100 | TNTYYLQtFGHNTMD | phosphorylation up-regulates activity | 21321328 | SIGNOR-263129 |
| STK39 | SLC12A1 | Ser91 | ASFHAYDsHTNTYYL | phosphorylation up-regulates activity | 21321328 | SIGNOR-263130 |
| OXSR1 | SLC12A1 | Thr105 | LQTFGHNtMDAVPKI | phosphorylation up-regulates activity | 21321328 | SIGNOR-276310 |
| STK39 | SLC12A1 | Thr95 | AYDSHTNtYYLQTFG | phosphorylation up-regulates activity | 21321328 | SIGNOR-263132 |
| STK39 | SLC12A1 | Thr105 | LQTFGHNtMDAVPKI | phosphorylation up-regulates activity | 21321328 | SIGNOR-263131 |
| WNK3 | SLC12A1 | – | phosphorylation up-regulates activity | 21613606 | SIGNOR-264626 | |
| STK39 | SLC12A1 | Thr105 | LQTFGHNtMDAVPKI | phosphorylation up-regulates activity | 21321328 | SIGNOR-276306 |
| STK39 | SLC12A1 | Ser130 | GPKVNRPsLLEIHEQ | phosphorylation up-regulates activity | 21321328 | SIGNOR-276305 |
| OXSR1 | SLC12A1 | Ser130 | GPKVNRPsLLEIHEQ | phosphorylation up-regulates activity | 21321328 | SIGNOR-276309 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| OXSR1 | phosphorylation up-regulates → | SLC12A1 PThr100 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-276311 |
| AMPK | phosphorylation up-regulates → | SLC12A1 PSer122 | phosphorylation up-regulates → | SLC12A1 | 17341212 | SIGNOR-263103 |
| OXSR1 | phosphorylation up-regulates → | SLC12A1 PSer91 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-276312 |
| STK39 | phosphorylation up-regulates → | SLC12A1 PThr100 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-276307 |
| STK39 | phosphorylation up-regulates → | SLC12A1 PSer91 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-276308 |
| STK39 | phosphorylation up-regulates → | SLC12A1 PThr100 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-263129 |
| STK39 | phosphorylation up-regulates → | SLC12A1 PSer91 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-263130 |
| OXSR1 | phosphorylation up-regulates → | SLC12A1 PThr105 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-276310 |
| STK39 | phosphorylation up-regulates → | SLC12A1 PThr95 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-263132 |
| STK39 | phosphorylation up-regulates → | SLC12A1 PThr105 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-263131 |
| STK39 | phosphorylation up-regulates → | SLC12A1 PThr105 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-276306 |
| STK39 | phosphorylation up-regulates → | SLC12A1 PSer130 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-276305 |
| OXSR1 | phosphorylation up-regulates → | SLC12A1 PSer130 | phosphorylation up-regulates → | SLC12A1 | 21321328 | SIGNOR-276309 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| OXSR1 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-276311 |
| AMPK | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-263103 |
| OXSR1 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-276312 |
| STK39 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-276307 |
| STK39 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-276308 |
| STK39 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-263129 |
| STK39 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-263130 |
| OXSR1 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-276310 |
| STK39 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-263132 |
| STK39 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-263131 |
| WNK3 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-264626 |
| STK39 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-276306 |
| STK39 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-276305 |
| OXSR1 | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-276309 |
