| Name | CDK13 |
| ID | Q14004 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 705-998 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK13 | EIF4B | Ser422 | RERSRTGsESSQTGT | phosphorylation up-regulates activity | 36882522 | SIGNOR-273115 |
| CDK13 | POLR2A | Ser1616 | TPQSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273054 |
| CDK13 | POLR2A | Ser1623 | SPTSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273047 |
| CDK13 | POLR2A | Ser1644 | SPTSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273042 |
| CDK13 | POLR2A | Ser1651 | SPTSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273040 |
| CDK13 | POLR2A | Ser1665 | SPTSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273041 |
| CDK13 | POLR2A | Ser1672 | SPTSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273046 |
| CDK13 | POLR2A | Ser1693 | SPTSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273045 |
| CDK13 | POLR2A | Ser1714 | SPTSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273044 |
| CDK13 | POLR2A | Ser1721 | SPTSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273048 |
| CDK13 | POLR2A | Ser1735 | SPTSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273043 |
| CDK13 | POLR2A | Ser1763 | TPTSPSYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273058 |
| CDK13 | POLR2A | Ser1784 | TPTSPNYsPTSPSYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273057 |
| CDK13 | POLR2A | Ser1861 | TPTSPKYsPTSPKYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273055 |
| CDK13 | POLR2A | Ser1868 | SPTSPKYsPTSPKYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273037 |
| CDK13 | POLR2A | Ser1875 | SPTSPKYsPTSPTYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273039 |
| CDK13 | POLR2A | Ser1878 | SPKYSPTsPTYSPTT | phosphorylation up-regulates activity | 32917631 | SIGNOR-273035 |
| CDK13 | POLR2A | Ser1882 | SPTSPTYsPTTPKYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273052 |
| CDK13 | POLR2A | Ser1889 | SPTTPKYsPTSPTYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273053 |
| CDK13 | POLR2A | Ser1896 | SPTSPTYsPTSPVYT | phosphorylation up-regulates activity | 32917631 | SIGNOR-273051 |
| CDK13 | POLR2A | Ser1910 | TPTSPKYsPTSPTYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273056 |
| CDK13 | POLR2A | Ser1917 | SPTSPTYsPTSPKYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273050 |
| CDK13 | POLR2A | Ser1924 | SPTSPKYsPTSPTYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273038 |
| CDK13 | POLR2A | Ser1931 | SPTSPTYsPTSPKGS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273049 |
| CDK13 | POLR2A | Ser1941 | SPKGSTYsPTSPGYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273034 |
| CDK13 | POLR2A | Ser1948 | SPTSPGYsPTSPTYS | phosphorylation up-regulates activity | 32917631 | SIGNOR-273036 |
| CDK13 | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation up-regulates activity | 36882522 | SIGNOR-273113 |
| CDK13 | SERINC5 | Ser360 | ARCCFCFsPGGEDTE | phosphorylation down-regulates quantity by destabilization | 34380030 | SIGNOR-278918 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK13 | phosphorylation up-regulates → | EIF4B PSer422 | phosphorylation up-regulates → | EIF4B | 36882522 | SIGNOR-273115 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1616 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273054 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1623 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273047 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1644 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273042 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1651 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273040 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1665 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273041 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1672 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273046 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1693 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273045 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1714 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273044 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1721 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273048 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1735 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273043 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1763 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273058 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1784 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273057 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1861 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273055 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1868 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273037 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1875 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273039 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1878 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273035 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1882 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273052 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1889 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273053 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1896 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273051 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1910 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273056 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1917 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273050 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1924 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273038 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1931 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273049 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1941 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273034 |
| CDK13 | phosphorylation up-regulates → | POLR2A PSer1948 | phosphorylation up-regulates → | POLR2A | 32917631 | SIGNOR-273036 |
| CDK13 | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation up-regulates → | EIF4EBP1 | 36882522 | SIGNOR-273113 |
| CDK13 | phosphorylation up-regulates → | SERINC5 PSer360 | phosphorylation down-regulates ⊣ | SERINC5 | 34380030 | SIGNOR-278918 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK13 | phosphorylation → up-regulates activity | EIF4B | SIGNOR-273115 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273054 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273047 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273042 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273040 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273041 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273046 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273045 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273044 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273048 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273043 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273058 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273057 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273055 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273037 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273039 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273035 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273052 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273053 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273051 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273056 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273050 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273038 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273049 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273034 |
| CDK13 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-273036 |
| CDK13 | phosphorylation → up-regulates activity | EIF4EBP1 | SIGNOR-273113 |
| CDK13 | phosphorylation down-regulates quantity by destabilization | SERINC5 | SIGNOR-278918 |