| Name | IL16 |
| ID | Q14005 |
| Role | substrate |
| Enzymatic Domains |
PDZ 1 216-302 PROSITE-ProRule
PDZ 2 355-440 PROSITE-ProRule
PDZ 3 1112-1197 PROSITE-ProRule
PDZ 4 1234-1319 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A2 | IL16 | Ser743 | MPLQPNAsLNEEEGT | phosphorylation up-regulates activity | 12450396 | SIGNOR-251009 |
| MAPK3 | IL16 | Ser845 | SIRQRISsFETFGSS | phosphorylation up-regulates | 14768064 | SIGNOR-121856 |
| MAPK1 | IL16 | Ser845 | SIRQRISsFETFGSS | phosphorylation up-regulates | 14768064 | SIGNOR-121852 |
| Gbeta | IL16 | – | phosphorylation up-regulates | 14768064 | SIGNOR-270056 | |
| CSNK2A1 | IL16 | Ser743 | MPLQPNAsLNEEEGT | phosphorylation up-regulates activity | 12450396 | SIGNOR-250905 |
| ERK1/2 | IL16 | – | phosphorylation up-regulates | 14768064 | SIGNOR-270168 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A2 | phosphorylation up-regulates → | IL16 PSer743 | phosphorylation up-regulates → | IL16 | 12450396 | SIGNOR-251009 |
| MAPK3 | phosphorylation up-regulates → | IL16 PSer845 | phosphorylation up-regulates → | IL16 | 14768064 | SIGNOR-121856 |
| MAPK1 | phosphorylation up-regulates → | IL16 PSer845 | phosphorylation up-regulates → | IL16 | 14768064 | SIGNOR-121852 |
| CSNK2A1 | phosphorylation up-regulates → | IL16 PSer743 | phosphorylation up-regulates → | IL16 | 12450396 | SIGNOR-250905 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A2 | phosphorylation → up-regulates activity | IL16 | SIGNOR-251009 |
| MAPK3 | phosphorylation → up-regulates | IL16 | SIGNOR-121856 |
| MAPK1 | phosphorylation → up-regulates | IL16 | SIGNOR-121852 |
| Gbeta | phosphorylation → up-regulates | IL16 | SIGNOR-270056 |
| CSNK2A1 | phosphorylation → up-regulates activity | IL16 | SIGNOR-250905 |
| ERK1/2 | phosphorylation → up-regulates | IL16 | SIGNOR-270168 |