Entity Details

Name CAMK1
ID Q14012
Role substrate
Enzymatic Domains
Protein kinase 20-276
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CAMKK1CAMK1Thr177
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DPGSVLStACGTPGYphosphorylation
up-regulates activity		8253780SIGNOR-250717
PPM1FCAMK1–dephosphorylation
down-regulates activity		11726284SIGNOR-277111
CAMKK2CAMK1Thr177
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DPGSVLStACGTPGYphosphorylation
up-regulates activity		7641687SIGNOR-250716
CAMK1CAMK1Thr177
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DPGSVLStACGTPGYphosphorylation
up-regulates activity		8253780SIGNOR-250612
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CAMKK1phosphorylation
up-regulates
→
CAMK1
PThr177		phosphorylation
up-regulates
→		CAMK18253780SIGNOR-250717
CAMKK2phosphorylation
up-regulates
→
CAMK1
PThr177		phosphorylation
up-regulates
→		CAMK17641687SIGNOR-250716
CAMK1phosphorylation
up-regulates
→
CAMK1
PThr177		phosphorylation
up-regulates
→		CAMK18253780SIGNOR-250612
Regulator Mechanism/Effect Target SIGNOR-ID
CAMKK1phosphorylation
→
up-regulates activity 		CAMK1SIGNOR-250717
PPM1Fdephosphorylation
→
down-regulates activity 		CAMK1SIGNOR-277111
CAMKK2phosphorylation
→
up-regulates activity 		CAMK1SIGNOR-250716
CAMK1phosphorylation
→
up-regulates activity 		CAMK1SIGNOR-250612