| Name | SCRIB |
| ID | Q14160 |
| Role | substrate |
| Enzymatic Domains |
PDZ 1 728-815 PROSITE-ProRule
PDZ 2 862-950 PROSITE-ProRule
PDZ 3 1004-1093 PROSITE-ProRule
PDZ 4 1100-1194 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | SCRIB | Ser1445 | PSPTSRQsPASPPPL | phosphorylation unknown | 20622900 | SIGNOR-263066 |
| ERK1/2 | SCRIB | Ser853 | LPLLPPEsPGPLRQR | phosphorylation unknown | 20622900 | SIGNOR-263065 |
| ERK1/2 | SCRIB | Ser1448 | TSRQSPAsPPPLGGG | phosphorylation unknown | 20622900 | SIGNOR-263064 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | SCRIB PSer1445 | phosphorylation down-regulates ⊣ | SCRIB | 20622900 | SIGNOR-263066 |
| ERK1/2 | phosphorylation up-regulates → | SCRIB PSer853 | phosphorylation down-regulates ⊣ | SCRIB | 20622900 | SIGNOR-263065 |
| ERK1/2 | phosphorylation up-regulates → | SCRIB PSer1448 | phosphorylation down-regulates ⊣ | SCRIB | 20622900 | SIGNOR-263064 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation → unknown | SCRIB | SIGNOR-263066 |
| ERK1/2 | phosphorylation → unknown | SCRIB | SIGNOR-263065 |
| ERK1/2 | phosphorylation → unknown | SCRIB | SIGNOR-263064 |