| Name | GIT2 |
| ID | Q14161 |
| Role | substrate |
| Enzymatic Domains |
Arf-GAP 1-124 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN12 | GIT2 | Tyr592 | NSTPESDyDNTPNDM | dephosphorylation down-regulates | 16317044 | SIGNOR-142719 |
| PTPN12 | GIT2 | Tyr286 | EELAMDVyDEVDRRE | dephosphorylation down-regulates | 16317044 | SIGNOR-142711 |
| PTPN12 | GIT2 | Tyr392 | QDNDQPDyDSVASDE | dephosphorylation down-regulates | 16317044 | SIGNOR-142715 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN12 | dephosphorylation down-regulates ⊣ | GIT2 PTyr592 | dephosphorylation up-regulates → | GIT2 | 16317044 | SIGNOR-142719 |
| PTPN12 | dephosphorylation down-regulates ⊣ | GIT2 PTyr286 | dephosphorylation up-regulates → | GIT2 | 16317044 | SIGNOR-142711 |
| PTPN12 | dephosphorylation down-regulates ⊣ | GIT2 PTyr392 | dephosphorylation up-regulates → | GIT2 | 16317044 | SIGNOR-142715 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN12 | dephosphorylation down-regulates | GIT2 | SIGNOR-142719 |
| PTPN12 | dephosphorylation down-regulates | GIT2 | SIGNOR-142711 |
| PTPN12 | dephosphorylation down-regulates | GIT2 | SIGNOR-142715 |