Entity Details

Name TRIM25
ID Q14258
Role substrate
Enzymatic Domains
B30.2/SPRY 439-630
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCTRIM25Tyr278NSKFDTIyQILLKKKphosphorylation
up-regulates activity		30100205SIGNOR-277405
MAP3K13TRIM25Ser12CPLAEELsCSICLEPphosphorylation
up-regulates quantity by stabilization		31186535SIGNOR-277456
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
TRIM25
PTyr278		phosphorylation
up-regulates
→		TRIM2530100205SIGNOR-277405
MAP3K13phosphorylation
up-regulates
→
TRIM25
PSer12		phosphorylation
up-regulates
→		TRIM2531186535SIGNOR-277456
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		TRIM25SIGNOR-277405
MAP3K13phosphorylation
→
up-regulates quantity by stabilization 		TRIM25SIGNOR-277456