Entity Details

Name FLNC
ID Q14315
Role substrate
Enzymatic Domains
Calponin-homology (CH) 1 36-142
PROSITE-ProRule
Calponin-homology (CH) 2 159-262
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKTFLNCSer2233
View in OncoXplorer
LGRERLGsFGSITRQphosphorylation
up-regulates quantity by stabilization		32444788SIGNOR-262616
PRKCAFLNCSer2236
View in OncoXplorer
ERLGSFGsITRQQEGphosphorylation
up-regulates quantity by stabilization		32444788SIGNOR-262617
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKTphosphorylation
up-regulates
→
FLNC
PSer2233		phosphorylation
up-regulates
→		FLNC32444788SIGNOR-262616
PRKCAphosphorylation
up-regulates
→
FLNC
PSer2236		phosphorylation
up-regulates
→		FLNC32444788SIGNOR-262617
Regulator Mechanism/Effect Target SIGNOR-ID
AKTphosphorylation
→
up-regulates quantity by stabilization 		FLNCSIGNOR-262616
PRKCAphosphorylation
→
up-regulates quantity by stabilization 		FLNCSIGNOR-262617