| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | PDE3A | Ser312 | SKSHRRTsLPCIPRE | phosphorylation up-regulates | 19261611 | SIGNOR-184448 |
| PRKACA | PDE3A | Ser312 | SKSHRRTsLPCIPRE | phosphorylation unknown | 16153182 | SIGNOR-140289 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | PDE3A PSer312 | phosphorylation up-regulates → | PDE3A | 19261611 | SIGNOR-184448 |
| PRKACA | phosphorylation up-regulates → | PDE3A PSer312 | phosphorylation down-regulates ⊣ | PDE3A | 16153182 | SIGNOR-140289 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation → up-regulates | PDE3A | SIGNOR-184448 |
| PRKACA | phosphorylation → unknown | PDE3A | SIGNOR-140289 |
