| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | BECN1 | Ser234 | AQYQREYsEFKRQQL | phosphorylation down-regulates activity | 31852899 | SIGNOR-279666 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | BECN1 PSer234 | phosphorylation down-regulates ⊣ | BECN1 | 31852899 | SIGNOR-279666 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation → down-regulates activity | BECN1 | SIGNOR-279666 |
