| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | BECN1 | Tyr233 | EAQYQREySEFKRQQ | phosphorylation down-regulates activity | 24034250 | SIGNOR-278357 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | phosphorylation up-regulates → | BECN1 PTyr233 | phosphorylation down-regulates ⊣ | BECN1 | 24034250 | SIGNOR-278357 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EGFR | phosphorylation → down-regulates activity | BECN1 | SIGNOR-278357 |
