| Name | NEDD9 |
| ID | Q14511 |
| Role | substrate |
| Enzymatic Domains |
SH3 3-65 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AURKA | NEDD9 | Ser296 | PVARRHQsLSPNHPP | phosphorylation up-regulates activity | 16184168 | SIGNOR-262654 |
| PTPN11 | NEDD9 | – | dephosphorylation down-regulates activity | 19275884 | SIGNOR-277083 | |
| AXL | NEDD9 | – | phosphorylation up-regulates activity | 32681075 | SIGNOR-278905 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AURKA | phosphorylation up-regulates → | NEDD9 PSer296 | phosphorylation up-regulates → | NEDD9 | 16184168 | SIGNOR-262654 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AURKA | phosphorylation → up-regulates activity | NEDD9 | SIGNOR-262654 |
| PTPN11 | dephosphorylation → down-regulates activity | NEDD9 | SIGNOR-277083 |
| AXL | phosphorylation → up-regulates activity | NEDD9 | SIGNOR-278905 |