Entity Details

Name SCN5A_Ser516
ID Q14524
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CAMK2ASCN5ASer516LSLTRGLsRTSMKPRphosphorylation
up-regulates activity		33410863SIGNOR-275770
CAMK2DSCN5ASer516LSLTRGLsRTSMKPRphosphorylation
down-regulates		22514276SIGNOR-197058
CAMK2BSCN5ASer516LSLTRGLsRTSMKPRphosphorylation
up-regulates activity		33410863SIGNOR-275773
CAMK2DSCN5ASer516LSLTRGLsRTSMKPRphosphorylation
up-regulates activity		33410863SIGNOR-275776
CAMK2GSCN5ASer516LSLTRGLsRTSMKPRphosphorylation
up-regulates activity		33410863SIGNOR-275779
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CAMK2Aphosphorylation
up-regulates
→
SCN5A
PSer516		phosphorylation
up-regulates
→		SCN5A33410863SIGNOR-275770
CAMK2Dphosphorylation
up-regulates
→
SCN5A
PSer516		phosphorylation
down-regulates
⊣		SCN5A22514276SIGNOR-197058
CAMK2Bphosphorylation
up-regulates
→
SCN5A
PSer516		phosphorylation
up-regulates
→		SCN5A33410863SIGNOR-275773
CAMK2Dphosphorylation
up-regulates
→
SCN5A
PSer516		phosphorylation
up-regulates
→		SCN5A33410863SIGNOR-275776
CAMK2Gphosphorylation
up-regulates
→
SCN5A
PSer516		phosphorylation
up-regulates
→		SCN5A33410863SIGNOR-275779
Regulator Mechanism/Effect Target SIGNOR-ID
CAMK2Aphosphorylation
→
up-regulates activity 		SCN5ASIGNOR-275770
CAMK2Dphosphorylation
img/direct_inhibition.png
down-regulates 		SCN5ASIGNOR-197058
CAMK2Bphosphorylation
→
up-regulates activity 		SCN5ASIGNOR-275773
CAMK2Dphosphorylation
→
up-regulates activity 		SCN5ASIGNOR-275776
CAMK2Gphosphorylation
→
up-regulates activity 		SCN5ASIGNOR-275779